购物车
- 全部删除
您的购物车当前为空
Anti-Phospho-RPS6KA5 (Ser376) Antibody (7N405)
还可以产品编号 TMAH-00961
别名 S6K-alpha-5, S6K alpha 5, RSK-like protein kinase, RSKL, RSK Like Protein Kinase, RLPK, Ribosomal protein S6 kinase alpha-5, Ribosomal Protein S6 Kinase Alpha 5, Ribosomal protein S6 kinase 90kD polypeptide 5, Phospho-RPS6KA5 (S376), Nuclear Mitogen And Stress Activated Protein Kinase 1, MSPK1, Mitogen and stress activated protein kinase 1, MGC1911, KS6A5_HUMAN, EC 2.7.11.1, 90 kDa ribosomal protein S6 kinase 5
Anti-Phospho-RPS6KA5 (Ser376) Antibody (7N405) 是一种抗体，靶向 Phospho-RPS6KA5 (Ser376)。Anti-Phospho-RPS6KA5 (Ser376) Antibody (7N405) 可用于 ELISA, IHC。
Anti-Phospho-RPS6KA5 (Ser376) Antibody (7N405)
Anti-Phospho-RPS6KA5 (Ser376) Antibody (7N405)
还可以产品编号 TMAH-00961 别名 S6K-alpha-5, S6K alpha 5, RSK-like protein kinase, RSKL, RSK Like Protein Kinase, RLPK, Ribosomal protein S6 kinase alpha-5, Ribosomal Protein S6 Kinase Alpha 5, Ribosomal protein S6 kinase 90kD polypeptide 5, Phospho-RPS6KA5 (S376), Nuclear Mitogen And Stress Activated Protein Kinase 1, MSPK1, Mitogen and stress activated protein kinase 1, MGC1911, KS6A5_HUMAN, EC 2.7.11.1, 90 kDa ribosomal protein S6 kinase 5
Anti-Phospho-RPS6KA5 (Ser376) Antibody (7N405) 是一种抗体，靶向 Phospho-RPS6KA5 (Ser376)。Anti-Phospho-RPS6KA5 (Ser376) Antibody (7N405) 可用于 ELISA, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,315 | 5日内发货 | |
| 100 μL | ¥ 2,185 | 5日内发货 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Phospho-RPS6KA5 (Ser376) Antibody (7N405) is an antibody targeting Phospho-RPS6KA5 (Ser376). Anti-Phospho-RPS6KA5 (Ser376) Antibody (7N405) can be used in ELISA, IHC. |
| 别名 | S6K-alpha-5, S6K alpha 5, RSK-like protein kinase, RSKL, RSK Like Protein Kinase, RLPK, Ribosomal protein S6 kinase alpha-5, Ribosomal Protein S6 Kinase Alpha 5, Ribosomal protein S6 kinase 90kD polypeptide 5, Phospho-RPS6KA5 (S376), Nuclear Mitogen And Stress Activated Protein Kinase 1, MSPK1, Mitogen and stress activated protein kinase 1, MGC1911, KS6A5_HUMAN, EC 2.7.11.1, 90 kDa ribosomal protein S6 kinase 5 |
| Ig Type | Rabbit IgG |
| 克隆号 | 7N405 |
| 交叉反应 | Human |
| 验证活性 | IHC image of TMAH-00961 diluted at 1:100 and staining in paraffin-embedded human bladder cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| 应用 | ELISA, IHC |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Nucleus. Cytoplasm. Note=Predominantly nuclear. Exported into cytoplasm in response to glucocorticoid. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes to RELA inhibition and repression of inflammatory gene expression. In skeletal myoblasts is required for phosphorylation of RELA at 'Ser-276' during oxidative stress. In erythropoietin-stimulated cells, is necessary for the 'Ser-727' phosphorylation of STAT3 and regulation of its transcriptional potential. Phosphorylates ETV1/ER81 at 'Ser-191' and 'Ser-216', and thereby regulates its ability to stimulate transcription, which may be important during development and breast tumor formation. Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A. Phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and EGF, which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN. May also phosphorylate 'Ser-28' of histone H3. Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 1 (HMGN1/HMG14). In lipopolysaccharide-stimulated primary macrophages, acts downstream of the Toll-like receptor TLR4 to limit the production of pro-inflammatory cytokines. Functions probably by inducing transcription of the MAP kinase phosphatase DUSP1 and the anti-inflammatory cytokine interleukin 10 (IL10), via CREB1 and ATF1 transcription factors. Plays a role in neuronal cell death by mediating the downstream effects of excitotoxic injury. Phosphorylates TRIM7 at 'Ser-107' in response to growth factor signaling via the MEK/ERK pathway, thereby stimulating its ubiquitin ligase activity. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human Phospho-RPS6KA5 (S376) |
| 抗原种属 | Human |
| 基因ID | 9252 |
| Uniprot ID | |
| 研究领域 | Signal Transduction |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-Phospho-RPS6KA5 (Ser376) Antibody (7N405) | purchase Anti-Phospho-RPS6KA5 (Ser376) Antibody (7N405) | Anti-Phospho-RPS6KA5 (Ser376) Antibody (7N405) cost | order Anti-Phospho-RPS6KA5 (Ser376) Antibody (7N405)
嗨！有任何问题？点我咨询
评论内容