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CAY10486
还可以产品编号 T36549Cas号 615264-52-3
Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of approximately 60 μM. It also inhibits copper-mediated oxidation of low density lipoproteins by about 28% at a concentration of 3 μM.
CAY10486
还可以产品编号 T36549Cas号 615264-52-3
Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of approximately 60 μM. It also inhibits copper-mediated oxidation of low density lipoproteins by about 28% at a concentration of 3 μM.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 mg | 待估 | 35日内发货 | |
| 10 mg | 待估 | 35日内发货 | |
| 25 mg | 待估 | 35日内发货 | |
| 50 mg | 待估 | 35日内发货 |
大包装 & 定制
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产品介绍
生物活性
化学信息
| 产品描述 | Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of approximately 60 μM. It also inhibits copper-mediated oxidation of low density lipoproteins by about 28% at a concentration of 3 μM. |
| 分子量 | 325.36 |
| 分子式 | C19H19NO4 |
| CAS No. | 615264-52-3 |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| 溶解度信息 | Ethanol: 20 mg/mL (61.47 mM), Sonication is recommended. DMSO:PBS (pH 7.2)(1:5): 0.5 mg/mL (1.54 mM), Sonication is recommended. DMSO: 30 mg/mL (92.21 mM), Sonication is recommended. DMF: 30 mg/mL (92.21 mM), Sonication is recommended. | |||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||
Ethanol/DMSO/DMF
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