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Anti-CXCL9 Antibody (2S324)
还可以产品编号 TMAY-01290
Anti-CXCL9 Antibody (2S324) 是一种 Mouse 抗体，靶向 CXCL9。Anti-CXCL9 Antibody (2S324) 可用于 ELISA,ELISA(Cap)。
Anti-CXCL9 Antibody (2S324)
Anti-CXCL9 Antibody (2S324)
还可以产品编号 TMAY-01290
Anti-CXCL9 Antibody (2S324) 是一种 Mouse 抗体，靶向 CXCL9。Anti-CXCL9 Antibody (2S324) 可用于 ELISA,ELISA(Cap)。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-CXCL9 Antibody (2S324) is a Mouse antibody targeting CXCL9. Anti-CXCL9 Antibody (2S324) can be used in ELISA,ELISA(Cap). |
| Ig Type | Monoclonal Mouse IgG2b |
| 克隆号 | 2S324 |
| 交叉反应 | Human |
| 应用 | ELISA,ELISA(Cap) |
| 推荐剂量 | ELISA: 1:1000-1:2000; ELISA(Cap): 1:250-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CXCL9 / MIG (rh CXCL9 / MIG; TMPY-02234; Q07325; Thr 23-Thr 125). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Chemokine (C-X-C motif) ligand 9 (CXCL9), also known as Monokine induced by gamma interferon (MIG), is a small cytokine belonging to the CXC chemokine family. The function of this chemokine has not been specifically defined; however, it is thought to be involved in T cell trafficking. CXCL9/MIG functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor found predominantly on T cells. CXCL9/MIG, together with CXCL10 and CXCL11, may activate CXCR3 by binding to it. CXCL9 serves as a cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. It has been observed that tumour endothelial cells secrete high levels of CXCL9 in all, and CXCL10 in most melanoma metastases. Experiment data represent novel mechanisms by which tumour cells in melanoma metastases might use the chemokine-expressing endothelium to leave the tumour and eventually to form additional metastases at distinct sites. Experiment results also improved that CXCL9/MIG plays an important role in CD4+ T lymphocyte recruitment and development of CAV, MOMA-2+ macrophages are the predominant recipient-derived source of CXCL9/MIG, and recipient CD4 lymphocytes are necessary for sustained CXCL9/MIG production and CAV development in this model. Neutralization of the chemokine CXCL9/MIG may have therapeutic potential for the treatment of chronic rejection after heart transplantation. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human CXCL9 / MIG protein (TMPY-02234) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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