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Anti-ELAC2/HPC2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ELAC2/HPC2。Anti-ELAC2/HPC2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-ELAC2/HPC2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ELAC2/HPC2。Anti-ELAC2/HPC2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-ELAC2/HPC2 Polyclonal Antibody is a Rabbit antibody targeting ELAC2/HPC2. Anti-ELAC2/HPC2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Dog,Rabbit) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Mitochondrion. Nucleus. Note=Mainly mitochondrial. |
| 组织特异性 | Widely expressed. Highly expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, testis and ovary. Weakly expressed in brain, lung, spleen, thymus, prostate, small intestine, colon and leukocytes. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | ELAC2 is a zinc phosphodiesterase which displays some tRNA 3' processing endonuclease activity. It is thought to be involved in tRNA maturation, acting by removing a 3' trailer from precursor tRNA. ELAC2 also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. A number of allelic variants have been investigated in hereditary prostate cancer. |
| 免疫原 | KLH conjugated synthetic peptide: human ELAC2 |
| 抗原种属 | Human |
| 基因名称 | ELAC2 |
| 基因ID | |
| 蛋白名称 | Zinc phosphodiesterase ELAC protein 2 |
| Uniprot ID | |
| 功能 | Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. |
| 分子量 | Theoretical: 92 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |