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Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody 3 是一种 Rabbit 抗体,靶向 Phospho-TOP2A (Ser1106)。Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody 3 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM。
Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody 3 是一种 Rabbit 抗体,靶向 Phospho-TOP2A (Ser1106)。Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody 3 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody 3 is a Rabbit antibody targeting Phospho-TOP2A (Ser1106). Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,ICC/IF,IF,FCM. |
| Ig Type | IgG |
| 交叉反应 | Human (predicted:Dog,Pig,Sheep,Danio) |
| 应用 | IHC-PIHC-FrICC/IFIFFCM |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; FCM: 1μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Nucleus > nucleoplasm. Generally located in the nucleoplasm. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. [provided by RefSeq, Jul 2010] |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human TOPO II Alpha around the phosphorylation site of Ser1106 |
| 抗原种属 | Human |
| 基因名称 | TOP2A |
| 基因ID | |
| 蛋白名称 | DNA topoisomerase 2-alpha |
| Uniprot ID | |
| 功能 | Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. |
| 分子量 | Theoretical: 174 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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