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Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody 3

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产品编号 TMAB-11385

Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody 3 是一种 Rabbit 抗体,靶向 Phospho-TOP2A (Ser1106)。Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody 3 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody 3

Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody 3

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-11385

Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody 3 是一种 Rabbit 抗体,靶向 Phospho-TOP2A (Ser1106)。Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody 3 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
50 μL
¥ 1,175
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100 μL
¥ 1,970
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200 μL
¥ 2,795
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产品介绍

生物活性
产品描述
Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody 3 is a Rabbit antibody targeting Phospho-TOP2A (Ser1106). Anti-Phospho-TOP2A (Ser1106) Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
交叉反应
Human (predicted:Dog,Pig,Sheep,Danio)
应用IHC-PIHC-FrICC/IFIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus > nucleoplasm. Generally located in the nucleoplasm.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. [provided by RefSeq, Jul 2010]
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human TOPO II Alpha around the phosphorylation site of Ser1106
抗原种属
Human
基因名称
TOP2A
基因ID
蛋白名称
DNA topoisomerase 2-alpha
Uniprot ID
功能
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.
化学信息
分子量Theoretical: 174 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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