Anti-CAV1 Antibody (8N14)

Name: Anti-CAV1 Antibody (8N14)
Brand: TargetMol
SKU: TMAH-00147
Rating: 4.5 (1 reviews)

还可以

产品编号 TMAH-00147

别名 VIP21, VIP 21, PPH3, OTTHUMP00000025031, MSTP085, LCCNS, CGL3, cell growth-inhibiting protein 32, Caveolin-1, Caveolin1, Caveolin 1 caveolae protein 22kDa, caveolin 1 beta isoform, caveolin 1 alpha isoform, caveolae protein, 22 kD, CAV 1, CAV, BSCL3

Anti-CAV1 Antibody (8N14) 是一种抗体，靶向 CAV1。Anti-CAV1 Antibody (8N14) 可用于 ELISA, WB, FC。

Anti-CAV1 Antibody (8N14)

还可以

产品编号 TMAH-00147 别名 VIP21, VIP 21, PPH3, OTTHUMP00000025031, MSTP085, LCCNS, CGL3, cell growth-inhibiting protein 32, Caveolin-1, Caveolin1, Caveolin 1 caveolae protein 22kDa, caveolin 1 beta isoform, caveolin 1 alpha isoform, caveolae protein, 22 kD, CAV 1, CAV, BSCL3

Anti-CAV1 Antibody (8N14) 是一种抗体，靶向 CAV1。Anti-CAV1 Antibody (8N14) 可用于 ELISA, WB, FC。

规格	价格	库存	数量
50 μL	¥ 1,305	5日内发货
100 μL	¥ 2,185	5日内发货

大包装 & 定制

加入购物车

TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

联系我们获取更多批次信息

资源下载

产品操作手册

产品介绍

生物活性

产品描述	Anti-CAV1 Antibody (8N14) is an antibody targeting CAV1. Anti-CAV1 Antibody (8N14) can be used in ELISA, WB, FC.
别名	VIP21, VIP 21, PPH3, OTTHUMP00000025031, MSTP085, LCCNS, CGL3, cell growth-inhibiting protein 32, Caveolin-1, Caveolin1, Caveolin 1 caveolae protein 22kDa, caveolin 1 beta isoform, caveolin 1 alpha isoform, caveolae protein, 22 kD, CAV 1, CAV, BSCL3
Ig Type	mIgG2a
克隆号	8N14
交叉反应	Human, Mouse, Rat
验证活性	1. Western Blot -Positive WB detected in:PC-3 whole cell lysate (20µg), A549 whole cell lysate (20µg), U251 whole cell lysate (20µg), Hela whole cell lysate (20µg), MCF-7 whole cell lysate (20µg), HEK293 whole cell lysate (20µg), Mouse Heart tissue lysate (20µg), Rat Heart tissue lysate (20µg) -All lanes: CAV1 antibody at 1:500 -Secondary: Goat polyclonal to mouse IgG at 1/50000 dilution -Predicted band size:20 kDa -Observed band size:20 kDa -Exposure time:120s 2. Overlay Peak curve showing Hela cells stained with TMAH-00147 (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/110^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-Mouse IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was mouse IgG (1ug/110^6 cells) used under the same conditions. Acquisition of >10,000 events was performed.
应用	ELISA, WB, FC
推荐剂量	WB:1:500-1:2000; FC:1:50-1:200.
抗体种类	Monoclonal
亚细胞定位	Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Golgi apparatus, trans-Golgi network. Note=Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae.
构建方式	Recombinant Antibody
纯化方式	Affinity-chromatography
性状	Liquid
缓冲液	Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
研究背景	May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway. Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation.

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Protein: Human CAV1 Protein
抗原种属	Human
基因ID	857
Uniprot ID	Q03135
研究领域	Cancer, Cardiovascular, Tags & Cell Markers, Metabolism, Signal transduction