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Survivin Protein, Human, Recombinant

Synonyms: IAP4, EPR-1, BIRC5, baculoviral IAP repeat containing 5, API4
货号 TMPY-03672Cas号 一键复制产品信息纯度:
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BIRC5, also known as Survivin and EPR-1, is a member of theIAP family. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but BIRC5 has only a single BIR domain. It is expressed cell cycle-dependently and highly expressed at mitosis. As a multitasking protein, BIRC5 has dual roles in promoting cell proliferation and preventing apoptosis. Survivin is a component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Survivin acts as an important regulator of the localization of this complex. It may counteract a default induction of apoptosis in G2/M phase.

Survivin Protein, Human, Recombinant

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货号 TMPY-03672

别名 IAP4, EPR-1, BIRC5, baculoviral IAP repeat containing 5, API4

BIRC5, also known as Survivin and EPR-1, is a member of theIAP family. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but BIRC5 has only a single BIR domain. It is expressed cell cycle-dependently and highly expressed at mitosis. As a multitasking protein, BIRC5 has dual roles in promoting cell proliferation and preventing apoptosis. Survivin is a component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Survivin acts as an important regulator of the localization of this complex. It may counteract a default induction of apoptosis in G2/M phase.

Survivin Protein, Human, Recombinant
规格价格库存数量
5 μg
¥ 365
3日内发货
10 μg
¥ 585
3日内发货
20 μg
¥ 958
3日内发货
50 μg
¥ 1,880
3日内发货
100 μg
¥ 3,170
现货
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选择批次:
纯度: > 95 % as determined by SDS-PAGE
颜色: 无色透明
性状: Solution
资源下载: COA重组蛋白用户指南

产品介绍

生物活性
产品描述
BIRC5, also known as Survivin and EPR-1, is a member of theIAP family. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but BIRC5 has only a single BIR domain. It is expressed cell cycle-dependently and highly expressed at mitosis. As a multitasking protein, BIRC5 has dual roles in promoting cell proliferation and preventing apoptosis. Survivin is a component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Survivin acts as an important regulator of the localization of this complex. It may counteract a default induction of apoptosis in G2/M phase.
生物活性
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
BIRC5, also known as Survivin and EPR-1, is a member of theIAP family. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but BIRC5 has only a single BIR domain. It is expressed cell cycle-dependently and highly expressed at mitosis. As a multitasking protein, BIRC5 has dual roles in promoting cell proliferation and preventing apoptosis. Survivin is a component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Survivin acts as an important regulator of the localization of this complex. It may counteract a default induction of apoptosis in G2/M phase.
种属
Human
表达系统
E. coli
标签
Tag Free
蛋白编号O15392
蛋白构建
A DNA sequence encoding the human BIRC5 (NP_001159.2) (Met1-Asp142) was expressed and purified with two additional amino acids (Gly & Pro) at the N-terminus. Predicted N terminal: Gly
蛋白纯度
> 95 % as determined by SDS-PAGE
蛋白性状
Solution
缓冲液
Supplied as sterile PBS, 20% glycerol, pH 7.4.
复溶方法
A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名
IAP4, EPR-1, BIRC5, baculoviral IAP repeat containing 5, API4
内毒素Please contact us for more information.
化学信息
分子量16.5 kDa (predicted); 19 kDa (reducing conditions)
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
  • 比活力 计算器

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

IAP-4IAP 4EPR1EPR 1BIRC-5BIRC 5API-4API 4
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