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Anti-gp130/IL6ST Antibody (9A213)
还可以产品编号 TMAY-01389
Anti-gp130/IL6ST Antibody (9A213) 是一种 Mouse 抗体，靶向 gp130/IL6ST。Anti-gp130/IL6ST Antibody (9A213) 可用于 FCM。
Anti-gp130/IL6ST Antibody (9A213)
Anti-gp130/IL6ST Antibody (9A213)
还可以产品编号 TMAY-01389
Anti-gp130/IL6ST Antibody (9A213) 是一种 Mouse 抗体，靶向 gp130/IL6ST。Anti-gp130/IL6ST Antibody (9A213) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-gp130/IL6ST Antibody (9A213) is a Mouse antibody targeting gp130/IL6ST. Anti-gp130/IL6ST Antibody (9A213) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG2a |
| 克隆号 | 9A213 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human IL6RB(CD130) expression on human whole blood Lymphocytes. Cells were stained with purified anti-Human IL6RB(CD130), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable Lymphocytes. |
| 应用 | FCM |
| 推荐剂量 | FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL6ST/gp130/CD130 (rh IL6ST/gp130/CD130; NP_002175.2Met1-Ile618). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta, or CD130) is a transmembrane protein that is the founding member of the class of all cytokine receptors. CD130/gp130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and Oncostatin M (OSM). CD130/gp130 functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. CD130/gp130 plays a critical role in regulating myocyte apoptosis. Alternatively, spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1, and BSF3 can utilize gp130 for initiating signal transmission. CD130/gp130 binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. CD130/gp130 may have a role in embryonic development. The type I OSM receptor is capable of transducing OSM-specific signaling events. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | PE |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human IL6ST/gp130/CD130 Protein |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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