Name: Dehydro Nifedipine
Brand: TargetMol
SKU: T36665
Price: 186 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 186

现货

5 mg

¥ 413

现货

10 mg

¥ 662

现货

25 mg

¥ 1,320

现货

50 mg

¥ 2,090

现货

100 mg

¥ 3,360

现货

200 mg

¥ 4,780

现货

产品介绍

生物活性

产品描述	Dehydro Nifedipine (BAY-b 4759) is the main metabolite of nifedipine in human plasma. Dehydro Nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM. Nifedipine is a calcium channel blocker used in the treatment of hypertension and angina. Dehydronifedipine is formed when it is metabolized by cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5.
靶点活性	Glucose uptake:130 μM
体外活性	Dehydro nifedipine 在PC-12细胞中抑制葡萄糖吸收，其半抑制浓度(IC50)值为130 μM[1]。
别名	去氢硝苯地平, BAY-b 4759

化学信息

分子量	344.32
分子式	C₁₇H₁₆N₂O₆
CAS No.	67035-22-7
Smiles	COC(=O)c1c(C)nc(C)c(C(=O)OC)c1-c1ccccc1[N+]([O-])=O
密度	1.284 g/cm3 (Predicted)
颜色	Yellow
物理性状	Solid

储存&溶解度

存储	store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
溶解度信息	Ethanol: 2.7 mg/mL (7.84 mM), Sonication is recommended. DMSO: 27 mg/mL (78.42 mM), Sonication is recommended. DMF: 30 mg/mL (87.13 mM), Sonication is recommended. DMSO:PBS (pH 7.2) (1:10): 0.1 mg/mL (0.29 mM), Sonication is recommended.

体内实验配液计算器