您的购物车当前为空
别名 THMD5, thiamin pyrophosphokinase 1, PP20, HTPK1
Thiamine pyrophosphokinase (TPK) produces thiamine pyrophosphate, a cofactor for a number of enzymes, including pyruvate dehydrogenase and 2-ketoglutarate dehydrogenase. Episodic encephalopathy type thiamine metabolism dysfunction (OMIM 614458) due to TPK1 mutations is a recently described rare disorder. The genomic variations in the fetal and maternal TPK1 gene could contribute to the variability of birth weight in normal humans.

Thiamine pyrophosphokinase (TPK) produces thiamine pyrophosphate, a cofactor for a number of enzymes, including pyruvate dehydrogenase and 2-ketoglutarate dehydrogenase. Episodic encephalopathy type thiamine metabolism dysfunction (OMIM 614458) due to TPK1 mutations is a recently described rare disorder. The genomic variations in the fetal and maternal TPK1 gene could contribute to the variability of birth weight in normal humans.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 472 | 6-8日内发货 | |
| 10 μg | ¥ 772 | 6-8日内发货 | |
| 20 μg | ¥ 1,270 | 5日内发货 | |
| 50 μg | ¥ 2,930 | 5日内发货 |
| 产品描述 | Thiamine pyrophosphokinase (TPK) produces thiamine pyrophosphate, a cofactor for a number of enzymes, including pyruvate dehydrogenase and 2-ketoglutarate dehydrogenase. Episodic encephalopathy type thiamine metabolism dysfunction (OMIM 614458) due to TPK1 mutations is a recently described rare disorder. The genomic variations in the fetal and maternal TPK1 gene could contribute to the variability of birth weight in normal humans. |
| 生物活性 | Kinase activity untested |
| 研究背景 | Thiamine pyrophosphokinase (TPK) produces thiamine pyrophosphate, a cofactor for a number of enzymes, including pyruvate dehydrogenase and 2-ketoglutarate dehydrogenase. Episodic encephalopathy type thiamine metabolism dysfunction (OMIM 614458) due to TPK1 mutations is a recently described rare disorder. The genomic variations in the fetal and maternal TPK1 gene could contribute to the variability of birth weight in normal humans. |
| 种属 | Human |
| 表达系统 | E. coli |
| 标签 | N-His |
| 蛋白编号 | AAH68460.1 |
| 蛋白构建 | A DNA sequence encoding the human TPK1 (AAH68460.1) (Met1-Ser243) was expressed with a polyhistidine tag at the N-terminus. Predicted N terminal: His |
| 蛋白纯度 | > 90 % as determined by SDS-PAGE |
| 蛋白性状 | Solution |
| 缓冲液 | Supplied as sterile PBS, pH 7.4. |
| 复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| 别名 | THMD5, thiamin pyrophosphokinase 1, PP20, HTPK1 |
| 内毒素 | Please contact us for more information. |
| 分子量 | 29.5 kDa (predicted); 27-32 kDa (reducing conditions) |
| 运输方式 | Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice. |
| 存储 | It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
对于不同动物的给药剂量换算,您也可以参考 更多