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Anti-HIF-1 beta Antibody (7D594) 是一种 Rabbit 抗体,靶向 HIF-1 beta。Anti-HIF-1 beta Antibody (7D594) 可用于 WB,IHC-P,IHC-Fr,IF,ICC/IF。
Anti-HIF-1 beta Antibody (7D594) 是一种 Rabbit 抗体,靶向 HIF-1 beta。Anti-HIF-1 beta Antibody (7D594) 可用于 WB,IHC-P,IHC-Fr,IF,ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,385 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
| 产品描述 | Anti-HIF-1 beta Antibody (7D594) is a Rabbit antibody targeting HIF-1 beta. Anti-HIF-1 beta Antibody (7D594) can be used in WB,IHC-P,IHC-Fr,IF,ICC/IF. |
| Ig Type | IgG |
| 克隆号 | 7D594 |
| 反应种属 | Human |
| 应用 | WBIHC-PIHC-FrIFICC/IF |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200; ICC/IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| 免疫原 | A synthesized peptide: human HIF 1 beta |
| 抗原种属 | Human |
| 基因名称 | ARNT |
| 基因ID | |
| 蛋白名称 | Aryl hydrocarbon receptor nuclear translocator |
| Uniprot ID | |
| 功能 | Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia. |
| 分子量 | Theoretical: 87 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |