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Anti-BCL11A Antibody (7U151) 是一种 Rabbit 抗体,靶向 BCL11A。Anti-BCL11A Antibody (7U151) 可用于 WB,ICC/IF,FCM。
Anti-BCL11A Antibody (7U151) 是一种 Rabbit 抗体,靶向 BCL11A。Anti-BCL11A Antibody (7U151) 可用于 WB,ICC/IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 790 | 5日内发货 | |
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-BCL11A Antibody (7U151) is a Rabbit antibody targeting BCL11A. Anti-BCL11A Antibody (7U151) can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG |
| 克隆号 | 7U151 |
| 反应种属 | Human (predicted:Mouse,Rat) |
| 应用 | WBICC/IFFCM |
| 推荐剂量 | WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Nucleus. Associates with the nuclear body. Colocalizes with SUMO1 and SENP2 in nuclear speckles. |
| 组织特异性 | Expressed at high levels in brain, spleen thymus, bone marrow and testis. Expressed in CD34-positive myeloid precursor cells, B-cells, monocytes and megakaryocytes. Expression is tightly regulated during B-cell development. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Associated with the BAF SWI/SNF chromatin remodeling complex.Binds to the 5'-TGACCA-3' sequence motif in regulatory regions of target genes, including a distal promoter of the HBG1 hemoglobin subunit gamma-1 gene.Involved in regulation of the developmental switch from gamma- to beta-globin, probably via direct repression of HBG1; hence indirectly repressing fetal hemoglobin (HbF) level. |
| 免疫原 | A synthesized peptide: human BCL 11A |
| 抗原种属 | Human |
| 基因名称 | BCL11A |
| 基因ID | |
| 蛋白名称 | B-cell lymphoma/leukemia 11A |
| Uniprot ID | |
| 功能 | Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis, is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1. |
| 分子量 | Theoretical: 91 kDa. Actual: 120 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |