Name: Selurampanel
Brand: TargetMol
SKU: T34609
Price: 798 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 798

现货

5 mg

¥ 1,870

现货

10 mg

¥ 2,690

现货

25 mg

¥ 4,180

现货

50 mg

¥ 5,950

现货

100 mg

¥ 8,230

现货

1 mL x 10 mM (in DMSO)

¥ 1,930

现货

生物活性

产品描述	Selurampanel (BGG492) is an orally active and selective competitive AMPA glutamate receptor antagonist, a quinazoline-dione sulfonamide. selurampanel is used in the study of epilepsy, migraine and tinnitus.
靶点活性	AMPA:190 nM
体内活性	Selurampanel (3 mg/kg i.v.) a mouse plasma half-life of 3.3 h is determined, with a moderate volume of distribution (Vdss=1.3 L/kg) and a low clearance of 5.4 mL/min▪kg.[5] Selurampanel potently and dose-dependently antagonizes maximal electroshock seizure-induced generalized tonic-clonic seizures in mice with an ED50 value around 7 mg/kg after 1 h pre-treatment.[5]
别名	BGG-492, BGG492, BGG 492

化学信息

分子量	377.42
分子式	C₁₆H₁₉N₅O₄S
CAS No.	912574-69-7
Smiles	C(C)(C)C1=C(C=C2C(=C1)NC(=O)N(NS(C)(=O)=O)C2=O)C=3N(C)N=CC3
密度	1.49 g/cm3 (Predicted)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 27.5 mg/mL (72.86 mM), Sonication is recommended.

溶液配制表

DMSO