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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-LXR alpha Antibody (4I723)

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货号 TMAB-08459

Anti-LXR alpha Antibody (4I723) 是一种 Rabbit 抗体，靶向 LXR alpha。Anti-LXR alpha Antibody (4I723) 可用于 WB,ICC/IF,FCM。

Anti-LXR alpha Antibody (4I723)

Anti-LXR alpha Antibody (4I723)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08459

Anti-LXR alpha Antibody (4I723) 是一种 Rabbit 抗体，靶向 LXR alpha。Anti-LXR alpha Antibody (4I723) 可用于 WB,ICC/IF,FCM。

规格价格库存数量
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,480
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

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产品描述
Anti-LXR alpha Antibody (4I723) is a Rabbit antibody targeting LXR alpha. Anti-LXR alpha Antibody (4I723) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
克隆号
4I723
反应种属
Human,Mouse,Rat
应用WBICC/IFFCM
推荐剂量
WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus (Potential).
组织特异性Visceral organs specific expression. Strong expression was found in liver, kidney and intestine followed by spleen and to a lesser extent the adrenals.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human LXR alpha
抗原种属
Human
基因名称
NR1H3
基因ID
10062
蛋白名称
Oxysterols receptor LXR-alpha
Uniprot ID
Q13133
功能
Orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
化学信息
分子量Theoretical: 50 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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