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Anti-Dio3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Dio3。Anti-Dio3 Polyclonal Antibody 可用于 WB。
Anti-Dio3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Dio3。Anti-Dio3 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-Dio3 Polyclonal Antibody is a Rabbit antibody targeting Dio3. Anti-Dio3 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Dog,Pig,Cow,Sheep) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein. |
| 组织特异性 | Expressed in placenta and several fetal tissues. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Dio3 belongs to the iodothyronine deiodinase family. It has an essential role for regulation of thyroid hormone inactivation during embryological development in that it catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3,3',5-triiodothyronine (T3) to inactive metabolites, 3,3',5'-triiodothyronine (RT3) and 3,3'-diiodothyronine (T2), respectively. Dio3 may play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones and has been linked to the development of consumptive hypothyroidism in both infants and adults. |
| 免疫原 | KLH conjugated synthetic peptide: human Dio3 |
| 抗原种属 | Human |
| 基因名称 | DIO3 |
| 基因ID | |
| 蛋白名称 | Thyroxine 5-deiodinase |
| Uniprot ID |
| 分子量 | Theoretical: 31 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |