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Anti-UBE2D4 Antibody (4Q854)
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产品编号 TMAY-02536
别名 ubiquitin-conjugating enzyme E2D 4 (putative), HBUCE1
Anti-UBE2D4 Antibody (4Q854) 是一种 Rabbit 抗体，靶向 UBE2D4。Anti-UBE2D4 Antibody (4Q854) 可用于 ELISA。
Anti-UBE2D4 Antibody (4Q854)
Anti-UBE2D4 Antibody (4Q854)
还可以产品编号 TMAY-02536 别名 ubiquitin-conjugating enzyme E2D 4 (putative), HBUCE1
Anti-UBE2D4 Antibody (4Q854) 是一种 Rabbit 抗体，靶向 UBE2D4。Anti-UBE2D4 Antibody (4Q854) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,289 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-UBE2D4 Antibody (4Q854) is a Rabbit antibody targeting UBE2D4. Anti-UBE2D4 Antibody (4Q854) can be used in ELISA. |
| 别名 | ubiquitin-conjugating enzyme E2D 4 (putative), HBUCE1 |
| Ig Type | Rabbit IgG |
| 克隆号 | 4Q854 |
| 交叉反应 | Human |
| 应用 | |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human UBE2D4 (rh UBE2D4; TMPY-02604; Q9Y2X8; Met1-Met1474). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | UBE2D4 is a member of the ubiquitin-conjugating E2 family whose members perform the second step in the ubiquitination reaction. Initially identified as the main process for protein degradation, ubiquitination is believed nowadays to be crucial for a wider range of cellular processes. The outcome of the ubiquitin-conjugation reaction, and thereby the fate of the substrate, is heavily dependent on the number of ubiquitin molecules attached and how these ubiquitin molecules are inter-connected. To deal with this complexity and to allow adequate ubiquitination in time and space, a highly sophisticated conjugation machinery has been developed. In a sequential manner, ubiquitin becomes activated by a ubiquitin-activating enzyme (E1), which then transfers the ubiquitin to a group of ubiquitin-conjugating enzymes (E2s). Next, ubiquitin-loaded E2s are interacting with ubiquitin-protein ligases (E3s) and ubiquitin is conjugated to substrates on recruitment by the E3. These three key enzymes are operating in a hierarchical system, wherein two E1s and 35 E2s have been found and hundreds of E3s have been identified in humans. It has been identified the UBE2D family (UBE2D1-4) as E2 partners for IDOL that support both autoubiquitination and IDOL-dependent ubiquitination of the LDLR in a cell-free system. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human UBE2D4 protein (TMPY-02604) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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