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Anti-UBE2D4 Antibody (4Q854)

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产品编号 TMAY-02536

Anti-UBE2D4 Antibody (4Q854) 是一种 Rabbit 抗体,靶向 UBE2D4。Anti-UBE2D4 Antibody (4Q854) 可用于 ELISA。

Anti-UBE2D4 Antibody (4Q854)

Anti-UBE2D4 Antibody (4Q854)

Rating icon 还可以
产品编号 TMAY-02536

Anti-UBE2D4 Antibody (4Q854) 是一种 Rabbit 抗体,靶向 UBE2D4。Anti-UBE2D4 Antibody (4Q854) 可用于 ELISA。

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产品介绍

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产品描述
Anti-UBE2D4 Antibody (4Q854) is a Rabbit antibody targeting UBE2D4. Anti-UBE2D4 Antibody (4Q854) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
4Q854
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human UBE2D4 (rh UBE2D4; TMPY-02604; Q9Y2X8; Met1-Met1474).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景UBE2D4 is a member of the ubiquitin-conjugating E2 family whose members perform the second step in the ubiquitination reaction. Initially identified as the main process for protein degradation, ubiquitination is believed nowadays to be crucial for a wider range of cellular processes. The outcome of the ubiquitin-conjugation reaction, and thereby the fate of the substrate, is heavily dependent on the number of ubiquitin molecules attached and how these ubiquitin molecules are inter-connected. To deal with this complexity and to allow adequate ubiquitination in time and space, a highly sophisticated conjugation machinery has been developed. In a sequential manner, ubiquitin becomes activated by a ubiquitin-activating enzyme (E1), which then transfers the ubiquitin to a group of ubiquitin-conjugating enzymes (E2s). Next, ubiquitin-loaded E2s are interacting with ubiquitin-protein ligases (E3s) and ubiquitin is conjugated to substrates on recruitment by the E3. These three key enzymes are operating in a hierarchical system, wherein two E1s and 35 E2s have been found and hundreds of E3s have been identified in humans. It has been identified the UBE2D family (UBE2D1-4) as E2 partners for IDOL that support both autoubiquitination and IDOL-dependent ubiquitination of the LDLR in a cell-free system.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human UBE2D4 protein (TMPY-02604)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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