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ITM2B Protein, Human, Recombinant (His)

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产品编号 TMPJ-01398

Integral Membrane Protein 2B (ITM2B) is expressed in the Golgi and on the cell surface. ITM2B forms homodimer through disulfide-linked interaction with SPPL2A, SPPL2B and APP. ITM2B is expressed in brain and the other tissues. Defects in ITM2B cause cerebral amyloid angiopathy ITM2B-related type 1(CAA-ITM2B1) and amyloid angiopathy ITM2B-related type 2(CAA-ITM2B2). CAA-ITM2B1 is characterized by amyloid deposition in the walls of cerebral blood vessels and neurodegeneration in the central nervous system. CAA-ITM2B2 characterized by amyloid deposition in the walls of the blood vessels of the cerebrum, choroid plexus, cerebellum, spinal cord and retina.

ITM2B Protein, Human, Recombinant (His)

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产品编号 TMPJ-01398

规格	价格	库存
5 μg	¥ 693	6-8日内发货
10 μg	¥ 1,170	6-8日内发货
20 μg	¥ 1,860	5日内发货
50 μg	¥ 3,470	5日内发货
100 μg	¥ 4,930	5日内发货
200 μg	¥ 7,350	5日内发货
500 μg	¥ 12,100	5日内发货
1 mg	¥ 17,300	5日内发货

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产品信息

生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述	Integral Membrane Protein 2B (ITM2B) is expressed in the Golgi and on the cell surface. ITM2B forms homodimer through disulfide-linked interaction with SPPL2A, SPPL2B and APP. ITM2B is expressed in brain and the other tissues. Defects in ITM2B cause cerebral amyloid angiopathy ITM2B-related type 1(CAA-ITM2B1) and amyloid angiopathy ITM2B-related type 2(CAA-ITM2B2). CAA-ITM2B1 is characterized by amyloid deposition in the walls of cerebral blood vessels and neurodegeneration in the central nervous system. CAA-ITM2B2 characterized by amyloid deposition in the walls of the blood vessels of the cerebrum, choroid plexus, cerebellum, spinal cord and retina.
种属	Human
表达系统	HEK293 Cells
标签	C-6xHis
蛋白编号	Q9Y287
别名	Transmembrane Protein BRI,Protein E25B,ITM2B,Integral Membrane Protein 2B,Immature BRI2,imBRI2,BRI2,BRI
氨基酸序列	Tyr76-Ser266
蛋白构建	Tyr76-Ser266
分子量	29-33 KDa (reducing condition)
内毒素	< 1 EU/μg by the LAL method.
缓冲液	Supplied as a 0.2 μm filtered solution of 20 mM Acetate, 10% Trehalose, 25 mM NaCl, 10% Glycerol, 0.05% Tween 80, pH 4.5.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Integral Membrane Protein 2B (ITM2B) is expressed in the Golgi and on the cell surface. ITM2B forms homodimer through disulfide-linked interaction with SPPL2A, SPPL2B and APP. ITM2B is expressed in brain and the other tissues. Defects in ITM2B cause cerebral amyloid angiopathy ITM2B-related type 1(CAA-ITM2B1) and amyloid angiopathy ITM2B-related type 2(CAA-ITM2B2). CAA-ITM2B1 is characterized by amyloid deposition in the walls of cerebral blood vessels and neurodegeneration in the central nervous system. CAA-ITM2B2 characterized by amyloid deposition in the walls of the blood vessels of the cerebrum, choroid plexus, cerebellum, spinal cord and retina.