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Anti-IL-17F Antibody (8H104) 是一种 Rabbit 抗体,靶向 IL-17F。Anti-IL-17F Antibody (8H104) 可用于 ELISA。
Anti-IL-17F Antibody (8H104) 是一种 Rabbit 抗体,靶向 IL-17F。Anti-IL-17F Antibody (8H104) 可用于 ELISA。
产品描述 | Anti-IL-17F Antibody (8H104) is a Rabbit antibody targeting IL-17F. Anti-IL-17F Antibody (8H104) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 8H104 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL-17F (rh IL-17F; TMPY-01898; NP_443104.1; Arg31-Gln163). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Interleukin-17F (IL-17F) is a cytokine that shares sequence similarity with IL17. The most notable role of IL-17 is its involvement in inducing and mediating proinflammatory responses. IL-17 is commonly associated with allergic responses. IL-17F is expressed by activated T cells and was expressed only in activated CD4+ T cells and activated monocytes. IL-17F has been shown to stimulate the production of several other cytokines, including IL6 and IL8. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. Recombinant human IL-17F did not stimulate the proliferation of hematopoietic progenitors or the migration of mature leukocytes. However, it markedly inhibited the angiogenesis of human endothelial cells and induced endothelial cells to produce IL-2, TGF-{beta}, and monocyte chemoattractant protein-1. IL-17F stimulates the production of other cytokines and granulocyte colony-stimulating factor and can regulate cartilage matrix turnover. IL-17F stimulates PBMC and T-cell proliferation. It also functions in inhibiting angiogenesis By similarity. IL-17F plays a role in the induction of neutrophilia in the lungs and the exacerbation of antigen-induced pulmonary allergic inflammation. |
偶联 | Unconjugated |
免疫原 | Recombinant Human IL-17F Protein (TMPY-01898) |
抗原种属 | Human |
研究领域 | Neuroinflammation |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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