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Anti-Apolipo E/APOE3 Antibody (7Q652)

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Anti-Apolipo E/APOE3 Antibody (7Q652)
产品编号 TMAC-00248
别名 Apolipoprotein E

Anti-Apolipo E/APOE3 Antibody (7Q652) 是一种 Rabbit 抗体,靶向 Apolipo E/APOE3。Anti-Apolipo E/APOE3 Antibody (7Q652) 可用于 WB,ICC/IF,IHC,IP。

Anti-Apolipo E/APOE3 Antibody (7Q652)

Anti-Apolipo E/APOE3 Antibody (7Q652)

Rating icon 还可以
Anti-Apolipo E/APOE3 Antibody (7Q652)
产品编号 TMAC-00248 别名 Apolipoprotein E

Anti-Apolipo E/APOE3 Antibody (7Q652) 是一种 Rabbit 抗体,靶向 Apolipo E/APOE3。Anti-Apolipo E/APOE3 Antibody (7Q652) 可用于 WB,ICC/IF,IHC,IP。

规格价格库存数量
50 μL
¥ 1,480
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100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-Apolipo E/APOE3 Antibody (7Q652) is a Rabbit antibody targeting Apolipo E/APOE3. Anti-Apolipo E/APOE3 Antibody (7Q652) can be used in WB,ICC/IF,IHC,IP.
别名Apolipoprotein E
Ig Type
IgG
克隆号
7Q652
交叉反应
Human,Mouse
验证活性
1. Western blot analysis of Apolipoprotein E on human kidney lysates using anti-Apolipoprotein E antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Apolipoprotein E antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Apolipoprotein E antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Apolipoprotein E antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-Apolipoprotein E antibody. Counter stained with hematoxylin.
应用
推荐剂量
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Apolipoprotein-E (apoE) is a protein component of plasma lipoproteins that mediates the binding, internalization and catabolism of lipoprotein particles. It can serve as a ligand for several lipoprotein receptors, including the LDL (ApoB/E) receptor and the hepatic apoE (chylomicron remnant) receptor. apoE is produced in most organs and occurs in all plasma lipoprotein fractions, constituting 10-20% of VLDL (very low density lipoprotein) and 1-2% of HDL (high density lipoprotein). Three major isoforms of apoE have been described in human (E2, E3 and E4) which differ by only one or two amino acids. Estrogen receptor has been shown to upregulate apoE gene expression via the ERa-mediated pathway, indicating a potential role for apoE in atherosclerosis. This is consistent with studies in mice in which plasma apoE levels were raised, thereby protecting the mice from diet-induced atherosclerosis. apoE has also been shown to be a potent inhibitor of proliferation and thus may play a role in angiogenesis, tumor cell growth and metastasis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 36 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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