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顶部生物活性储存和溶解信息计算器

Anti-CLEC4C Antibody (7F312)

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产品编号 TMAH-00284

别名 HECL, DLEC, CLECSF7, CLECSF11, CLEC4C, CD303, BDCA-2, BDCA2

Anti-CLEC4C Antibody (7F312) 是一种抗体，靶向 CLEC4C。Anti-CLEC4C Antibody (7F312) 可用于 ELISA。

Anti-CLEC4C Antibody (7F312)

Anti-CLEC4C Antibody (7F312)

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产品编号 TMAH-00284 别名 HECL, DLEC, CLECSF7, CLECSF11, CLEC4C, CD303, BDCA-2, BDCA2

Anti-CLEC4C Antibody (7F312) 是一种抗体，靶向 CLEC4C。Anti-CLEC4C Antibody (7F312) 可用于 ELISA。

规格价格库存数量
50 μL
¥ 1,305
5日内发货
100 μL
¥ 2,195
5日内发货
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产品介绍

生物活性
产品描述
Anti-CLEC4C Antibody (7F312) is an antibody targeting CLEC4C. Anti-CLEC4C Antibody (7F312) can be used in ELISA.
别名HECL, DLEC, CLECSF7, CLECSF11, CLEC4C, CD303, BDCA-2, BDCA2
Ig Type
Human IgG1
克隆号
7F312
交叉反应
Human
验证活性
The Binding Activity of CLEC4C with anti-CLEC4C antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CLEC4C at 2 μg/mL can bind Anti-CLEC4C recombinant antibody，the EC50 is 7.658-12.99 ng/mL.
应用ELISA
抗体种类
Monoclonal
亚细胞定位Cell membrane; Single-pass type II membrane protein.
组织特异性Expressed in plasmacytoid dendritic cells (PDCs). Constitutively expressed in immature monocyte-derived dendritic cells (iMDDC) and is significantly down-regulated upon maturation with LPS but not with TNF-alpha.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
研究背景Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human CLEC4C Protein
抗原种属
Human
基因名称
CLEC4C
基因ID
170482
Uniprot ID
Q8WTT0
研究领域
Others
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

CLECSF-7CLECSF-11CLECSF 7CLECSF 11CD-303CD 303BDCA 2

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