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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ICOS Antibody (4Y416)

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货号 TMAB-07483

Anti-ICOS Antibody (4Y416) 是一种 Rabbit 抗体，靶向 ICOS。Anti-ICOS Antibody (4Y416) 可用于 WB,ICC/IF,FCM。

Anti-ICOS Antibody (4Y416)

Anti-ICOS Antibody (4Y416)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07483

Anti-ICOS Antibody (4Y416) 是一种 Rabbit 抗体，靶向 ICOS。Anti-ICOS Antibody (4Y416) 可用于 WB,ICC/IF,FCM。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-ICOS Antibody (4Y416) is a Rabbit antibody targeting ICOS. Anti-ICOS Antibody (4Y416) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
克隆号
4Y416
反应种属
Human,Mouse
应用WBICC/IFFCM
推荐剂量
WB: 1:1000-2000; ICC/IF: 1:50-200; FCM: 1μg/Test
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Isoform 1: Cell membrane; Single-pass type I membrane protein (Potential).Isoform 2: Secreted (Potential).
组织特异性Activated T-cells. Highly expressed on tonsillar T-cells, which are closely associated with B-cells in the apical light zone of germinal centers, the site of terminal B-cell maturation. Expressed at lower levels in thymus, lung, lymph node and peripheral blood leukocytes. Expressed in the medulla of fetal and newborn thymus.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.[provided by RefSeq, Jul 2008].
抗原信息
免疫原
A synthesized peptide: human ICOS
抗原种属
Human
基因名称
ICOS
基因ID
29851
蛋白名称
Inducible T-cell costimulator
Uniprot ID
Q9Y6W8
功能
Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).
化学信息
分子量Theoretical: 20 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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