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PCSK9 Protein, Human, Recombinant (His & HA & Avi), Biotinylated

PCSK9 Protein, Human, Recombinant (His & HA & Avi), Biotinylated

产品编号 TMPJ-00369
别名: Subtilisin/Kexin-Like Protease PC9, PCSK9, NARC1, Proprotein Convertase Subtilisin/Kexin Type 9, PC9, Neural Apoptosis-Regulated Convertase 1, Proprotein Convertase 9, NARC-1

PCSK9 Protein, Human, Recombinant (His & HA & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-8xHis-HA-Avi tag. The predicted molecular weight is 18 and 58-70 and 90-150 KDa and the accession number is Q8NBP7.

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PCSK9 Protein, Human, Recombinant (His & HA & Avi), Biotinylated
规格 价格/CNY 货期 数量
20 μg ¥ 2,260 5日内发货
100 μg ¥ 6,130 5日内发货
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产品目录号及名称: PCSK9 Protein, Human, Recombinant (His & HA & Avi), Biotinylated (TMPJ-00369)
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产品描述 PCSK9 Protein, Human, Recombinant (His & HA & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-8xHis-HA-Avi tag. The predicted molecular weight is 18 and 58-70 and 90-150 KDa and the accession number is Q8NBP7.
种属 Human
表达系统 HEK293 Cells
标签 C-8xHis-HA-Avi
蛋白编号 Q8NBP7
别名 Subtilisin/Kexin-Like Protease PC9, PCSK9, NARC1, Proprotein Convertase Subtilisin/Kexin Type 9, PC9, Neural Apoptosis-Regulated Convertase 1, Proprotein Convertase 9, NARC-1
氨基酸序列 Gln31-Gln692(Val474Ile,Gly670Glu)
蛋白构建 Gln31-Gln692(Val474Ile,Gly670Glu)
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 18&58-70&90-150 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 20% Glycerol, pH 7.4.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Human Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. Inhibition of PCSK9 function by preventing PCSK9/LDLR interaction is currently being explored as a means of lowering cholesterol levels. PCSK9 also binds to apolipoprotein receptor 2 (ApoER2), and play a role in the neural development.

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Keywords

PCSK9 Protein, Human, Recombinant (His & HA & Avi), Biotinylated Subtilisin/Kexin-Like Protease PC9 PCSK9 NARC1 PC-9 Proprotein Convertase Subtilisin/Kexin Type 9 PC 9 PCSK-9 NARC 1 PC9 Neural Apoptosis-Regulated Convertase 1 Proprotein Convertase 9 NARC-1 PCSK 9 recombinant recombinant-proteins proteins protein

 

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