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Anti-HSF4 Antibody (1L976)

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Anti-HSF4 Antibody (1L976)
产品编号 TMAC-02026
别名 Marner, HSTF 4, HSF4_HUMAN, HSF4, HSF 4, hHSF4, Heat shock transcription factor 4, Heat shock factor protein 4, CTM, Cataract

Anti-HSF4 Antibody (1L976) 是一种 Mouse 抗体,靶向 HSF4。Anti-HSF4 Antibody (1L976) 可用于 WB,FCM。

Anti-HSF4 Antibody (1L976)

Anti-HSF4 Antibody (1L976)

Rating icon 还可以
Anti-HSF4 Antibody (1L976)
产品编号 TMAC-02026 别名 Marner, HSTF 4, HSF4_HUMAN, HSF4, HSF 4, hHSF4, Heat shock transcription factor 4, Heat shock factor protein 4, CTM, Cataract

Anti-HSF4 Antibody (1L976) 是一种 Mouse 抗体,靶向 HSF4。Anti-HSF4 Antibody (1L976) 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,990
5日内发货
100 μL
¥ 2,985
5日内发货
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产品介绍

生物活性
产品描述
Anti-HSF4 Antibody (1L976) is a Mouse antibody targeting HSF4. Anti-HSF4 Antibody (1L976) can be used in WB,FCM.
别名Marner, HSTF 4, HSF4_HUMAN, HSF4, HSF 4, hHSF4, Heat shock transcription factor 4, Heat shock factor protein 4, CTM, Cataract
交叉反应
Human
验证活性
1. Western blot analysis of HSF4 on human HSF4 recombinant protein using anti-HSF4 antibody at 1/1,000 dilution.
2. Flow cytometric analysis of HeLa cells with HSF4 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
应用
推荐剂量
WB: 1:500-1000; FCM: 1:100-200
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
研究背景Heat shock transcription factors (HSF, also designated HSTF) 1 and 2 are involved in this regulation. HSF1 and HSF2 are upregulated by estrogen, at both the mRNA and protein level. HSF1 is normally found as a monomer, whose transcriptional activity is repressed by constitutive phosphorylation. Upon activation, HSF1 forms trimers, gains DNA binding activity and is translocated to the nucleus. HSF2 activity is associated with differentiation and development, and, like HSF1, binds DNA as a trimer. HSF4 exists as two splice variants and is expressed in heart, brain and skeletal muscle as a homotrimer. HSF4a does not contain a DNA-binding domain and inhibits the formation of HSF1 nuclear bodies, thus repressing HSF1 mediated transcription. HSF4b does contain a DNA-binding domain and colocalizes with HSF1 nuclear bodies after heat shock.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 53 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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