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Anti-HSF4 Antibody (1L976) 是一种 Mouse 抗体,靶向 HSF4。Anti-HSF4 Antibody (1L976) 可用于 WB,FCM。
Anti-HSF4 Antibody (1L976) 是一种 Mouse 抗体,靶向 HSF4。Anti-HSF4 Antibody (1L976) 可用于 WB,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,990 | 5日内发货 | |
100 μL | ¥ 2,985 | 5日内发货 |
产品描述 | Anti-HSF4 Antibody (1L976) is a Mouse antibody targeting HSF4. Anti-HSF4 Antibody (1L976) can be used in WB,FCM. |
别名 | Marner, HSTF 4, HSF4_HUMAN, HSF4, HSF 4, hHSF4, Heat shock transcription factor 4, Heat shock factor protein 4, CTM, Cataract |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of HSF4 on human HSF4 recombinant protein using anti-HSF4 antibody at 1/1,000 dilution. 2. Flow cytometric analysis of HeLa cells with HSF4 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
应用 | |
推荐剂量 | WB: 1:500-1000; FCM: 1:100-200 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
研究背景 | Heat shock transcription factors (HSF, also designated HSTF) 1 and 2 are involved in this regulation. HSF1 and HSF2 are upregulated by estrogen, at both the mRNA and protein level. HSF1 is normally found as a monomer, whose transcriptional activity is repressed by constitutive phosphorylation. Upon activation, HSF1 forms trimers, gains DNA binding activity and is translocated to the nucleus. HSF2 activity is associated with differentiation and development, and, like HSF1, binds DNA as a trimer. HSF4 exists as two splice variants and is expressed in heart, brain and skeletal muscle as a homotrimer. HSF4a does not contain a DNA-binding domain and inhibits the formation of HSF1 nuclear bodies, thus repressing HSF1 mediated transcription. HSF4b does contain a DNA-binding domain and colocalizes with HSF1 nuclear bodies after heat shock. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 53 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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