Anti-Siglec-3/CD33 Polyclonal Antibody is a Rabbit antibody targeting Siglec-3/CD33. Anti-Siglec-3/CD33 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA.

IgG

Mouse

Sample:
Lane 1: Bone (Mouse) Lysate at 40 μg
Lane 2: LympHnode (Mouse) Lysate at 40 μg
Primary: Anti-CD33 (TMAB-01688) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 40/37 kDa
Observed band size: 65 kDa

WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000

Polyclonal

KLH conjugated synthetic peptide: mouse CD33

Mouse

CD33

Myeloid cell surface antigen CD33

Myeloid Cells,Human Lineage Negative

Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).