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Anti-FGF1 Polyclonal Antibody 3

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货号 TMAB-05980

Anti-FGF1 Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 FGF1。Anti-FGF1 Polyclonal Antibody 3 可用于 IHC-P,IHC-Fr,IF。

Anti-FGF1 Polyclonal Antibody 3

Anti-FGF1 Polyclonal Antibody 3

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Rating icon 还可以
货号 TMAB-05980

Anti-FGF1 Polyclonal Antibody 3 是一种 Rabbit 抗体，靶向 FGF1。Anti-FGF1 Polyclonal Antibody 3 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
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100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-FGF1 Polyclonal Antibody 3 is a Rabbit antibody targeting FGF1. Anti-FGF1 Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Pig,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytosol. Nucleus. Note=Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1 (By similarity). Binding of exogenous FGF1 to FGFR facilitates endocytosis followed by translocation of FGF1 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as LRRC59.
组织特异性Predominantly expressed in kidney and brain. Detected at much lower levels in heart and skeletal muscle.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景FGF1 also designated Heparin-binding growth factor 1 precursor (HBGF-1) ; Acidic fibroblast growth factor (aFGF). heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. Subunit si monomer.FGF1 belongs to the heparin-binding growth factors family. may play a role in neurite outgrowth; may regulate cell differentiation in the nervous system; may act in synergy with fibronectin to enhance neuronal cell adhesion.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FGF1
抗原种属
Human
基因名称
FGF1
基因ID
2246
蛋白名称
Fibroblast growth factor 1
Uniprot ID
P05230
功能
The heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro.
化学信息
分子量Theoretical: 16 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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