规格

价格

库存

数量

20 μg

¥ 5,930

待询

生物活性

产品描述	ALK-7 Protein, Human, Recombinant (GST) is expressed in Baculovirus-Insect Cells. The accession number is Q8NER5.
生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it.
研究背景	ALK-7, also known as ALK7 and ACVR1C, belongs to the ALK family. It is a type I receptor for the TGFB family of signaling molecules. TGF-β is the prototype of a protein superfamily which, in humans, contains at least 35 members, including activins, inhibins, bone morphogenetic proteins, growth/differentiation factors, and Müllerian inhibiting substance. ALK-7 is a serine-threonine kinase that can cause the activation of one of the SMAD signal transducers, SMAD2. ALK-7 has a ligand known as Nodal. Nodal stimulates the secretion of TIMP-1 and inhibits matrix metalloproteinases MMP-2 and MMP-9 activity. The overexpression of Nodal or constitutively active ALK-7 decreases cell migration and invasion, whereas knock-down of Nodal and ALK-7 has the opposite effects.
种属	Human
表达系统	Baculovirus-Insect Cells
标签	N-GST
蛋白编号	Q8NER5
蛋白构建	Recombinant human ALK7 (135-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
蛋白纯度	>70% as determined by SDS-PAGE.
蛋白性状	Solution
缓冲液	Supplied as sterile 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
别名	ALK-7, ALK7, ACVR1C, ACTR-IC, Activin receptor type-1C

化学信息

分子量

~68 kDa

储存&溶解度

运输方式

Enzymes are highly recommended to be shipped at frozen temperature with dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products.

存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

ALK-7 Protein, Human, Recombinant (GST)

ALK-7 Protein, Human, Recombinant (GST)

产品介绍

引用文献

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