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Anti-CtBP1 Antibody (2M770)
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产品编号 TMAC-01006
别名 MGC104684, C-terminal-binding protein 1, CTBP1_HUMAN, CtBP 1, CTBP, C terminal binding protein 1, brefeldin A- ribosylated substrate, BARS
Anti-CtBP1 Antibody (2M770) 是一种 Rabbit 抗体，靶向 CtBP1。Anti-CtBP1 Antibody (2M770) 可用于 WB,IHC,ICC,IF,IP。
Anti-CtBP1 Antibody (2M770)
Anti-CtBP1 Antibody (2M770)
还可以产品编号 TMAC-01006 别名 MGC104684, C-terminal-binding protein 1, CTBP1_HUMAN, CtBP 1, CTBP, C terminal binding protein 1, brefeldin A- ribosylated substrate, BARS
Anti-CtBP1 Antibody (2M770) 是一种 Rabbit 抗体，靶向 CtBP1。Anti-CtBP1 Antibody (2M770) 可用于 WB,IHC,ICC,IF,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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产品介绍
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偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-CtBP1 Antibody (2M770) is a Rabbit antibody targeting CtBP1. Anti-CtBP1 Antibody (2M770) can be used in WB,IHC,ICC,IF,IP. |
| 别名 | MGC104684, C-terminal-binding protein 1, CTBP1_HUMAN, CtBP 1, CTBP, C terminal binding protein 1, brefeldin A- ribosylated substrate, BARS |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of CtBP1 on PC-3M cell lysate using anti-CtBP1 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-CtBP1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-CtBP1 antibody. Counter stained with hematoxylin. 4. ICC staining CtBP1 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-100; IP: 1:10-50 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | CtBP1 is a cellular phosphoprotein that associates with various proteins and functions as a corepressor of transcription. CtBP1 and the related protein CtBP2 are characterized as C-terminal binding protein of adenovirus E1A, and they preferentially associate with the E1A via a 5-amino acid motif, PLDLS, to repress E1A induced oncogenesis and cellular transformation. CtBP1 is expressed from embryo to adult, but CtBP2 is mainly expressed during embryogenesis. During skeletal and T-cell development, CtBP1 and CtBP2 associate with the PLDLSL domain of δEF1, a cellular zinc finger-homeodomain protein, and thereby enhances δEF1 induced transcriptional silencing. In addition, CtBP complexes with CtIP, a protein that recognizes distinctly different protein motifs from CtBP. CtIP binds to the BRCT repeats within the breast cancer gene BRCA1 and enables CtBP to influence BRCA1 activity. CtIP/CtBP binding to BRCA1 inhibits the transactivation of the p21 promoter, and it is critical for regulating p21 transcription in response to DNA damage. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: human CtBP1 aa 300-500 |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 47 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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