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Pentetic Acid

Name: Pentetic Acid
Brand: TargetMol
SKU: T0420
Price: 148 CNY
Availability: InStock
Rating: 5 (10 reviews)

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货号 T0420Cas号 67-43-6

别名 二乙烯三胺五醋酸, DTPA, diethylenetriaminepentaacetic acid, Detarex, Detapac, Acidum penteticum

Pentetic Acid (Detarex) 是一种能够构建磁性吸附剂的化合物，能够去除复杂废水中的重金属及染料。

Pentetic Acid

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货号 T0420 别名 二乙烯三胺五醋酸, DTPA, diethylenetriaminepentaacetic acid, Detarex, Detapac, Acidum penteticumCas号 67-43-6

Pentetic Acid (Detarex) 是一种能够构建磁性吸附剂的化合物，能够去除复杂废水中的重金属及染料。

规格	价格	库存
50 mg	¥ 148	现货
100 mg	¥ 282	现货
200 mg	¥ 385	现货
500 mg	¥ 639	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

选择批次:

纯度: ≥95%

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COA HNMR 产品操作手册

产品介绍

Pentetic Acid AI Summary

Pentetic Acid demonstrates various dissociation constants (pKa values) ranging from 2.0 to 10.48 at 25 degrees Celsius, indicative of its potential ionization and acidity characteristics. It shows a high stability constant (log K = 22.4) for Yttrium(III) and Gadolinium(III), suggesting strong chelating properties. The compound has notable biodistribution in tissues such as tumors, liver, and kidneys when tested in mice and rats, indicating its potential for targeted imaging or therapeutic applications. In cytotoxicity assays, it exhibits an IC50 value of 264500.0 nM against human HeLa cells and 39100.0 nM against human HT29 cells, while showing antiproliferative activity against human HepG2 cells with an IC50 value of 38300.0 nM. Additionally, Pentetic Acid displays a broad spectrum of bioactivities, inhibiting various enzymes such as Human Jumonji Domain Containing 2E (JMJD2E), Tyrosyl-DNA Phosphodiesterase 1 (TDP1), and Giardia Lamblia's Fructose-1,6-bisphosphate Aldolase, among others. It also exhibits antimicrobial and antiviral activities, including against SARS-CoV-2 with IC50 values indicating moderate to weak potency. Moreover, it shows metal chelating activity with a significant stability constant of Fe3+-compound complex (log K = 28.6). The compound exhibits minimal toxicity, evidenced by the absence of drug-induced liver injury in humans and only low inhibition of cell viability in SARS-CoV-2 infected Vero E6 cells. Finally, it interacts with multiple receptors and enzymes with varying degrees of inhibition and activation, signifying its versatile bioactivity profile..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Pentetic Acid (Detarex) is an edetate and a chelating agent used in preparing radiopharmaceuticals.
别名	二乙烯三胺五醋酸, DTPA, diethylenetriaminepentaacetic acid, Detarex, Detapac, Acidum penteticum

化学信息

分子量	393.35
分子式	C₁₄H₂₃N₃O₁₀
CAS No.	67-43-6
Smiles	OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CCN(CC(O)=O)CC(O)=O
密度	Ca. 625 g/L. Temperature:20 °C.

储存&溶解度

存储

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 1.17 mg/mL (2.97 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5423 mL	12.7113 mL	25.4227 mL	127.1133 mL

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法： 取 100 μL DMSO 母液，添加 400 μL PEG300 混匀澄清，再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH₂O 混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD，玉米油等，均可在TargetMol网站点击购买。

剂量转换

对于不同动物的给药剂量换算，您也可以参考更多

关键词

wastewater Pentetic Acid metal magnetic adsorbent Inhibitor inhibit dye chelating agent

Pentetic Acid

Pentetic Acid

Pentetic Acid 相关产品

产品介绍

计算器

体内实验配液计算器

剂量转换

引用文献

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