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Anti-FcRH2 Polyclonal Antibody

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货号 TMAB-05953

Anti-FcRH2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FcRH2。Anti-FcRH2 Polyclonal Antibody 可用于 WB。

Anti-FcRH2 Polyclonal Antibody

Anti-FcRH2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05953

Anti-FcRH2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FcRH2。Anti-FcRH2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-FcRH2 Polyclonal Antibody is a Rabbit antibody targeting FcRH2. Anti-FcRH2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane.
组织特异性Expressed in the secondary lymphoid organs, spleen and lymph node. Expression is limited to the mature B-cell lines. Highly expressed in CD19 and within the mantle zones of the tonsil tissue. Isoform 2 is expressed in the spleen, peripheral blood and bone marrow. Isoform 2 and isoform 4 are expressed in B-cell lines. Preferentially expressed in memory B-cells (at protein level).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The Fc receptor homolog (FcRH) family of proteins are related to the classical Fc receptors (FcR) and belong to the immunoglobulin receptor superfamily. The proteins in the FcRH family are type I transmembrane glycoproteins and consist of FcRH1-FcRH6. The genes encoding the human FcRH proteins map to chromosome 1, near the related FCR genes. The FcRH proteins, which are involved in immune system regulation, have immunoreceptor-tyrosine inhibitory motifs in their cytoplasmic domains. Mutations in the gene encoding for the FcRH proteins may be associated with systemic lupus erythematosus, autoimmune thyroid disease and rheumatoid arthritis. The FcRH genes are expressed primarily, although not exclusively, by mature B lineage cells, and may serve important regulatory roles in normal and neoplastic B cell development.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FcRH2
抗原种属
Human
基因名称
FCRL2
基因ID
79368
蛋白名称
Fc receptor-like protein 2
Uniprot ID
Q96LA5
功能
May have an regulatory role in normal and neoplastic B cell development.
化学信息
分子量Theoretical: 53 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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