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Anti-CD299 Monoclonal Antibody (2X91) 是一种 Mouse 抗体,靶向 CD299。Anti-CD299 Monoclonal Antibody (2X91) 可用于 WB,FCM。
别名 L-SIGN, LSIGN, HP10347, DC-SIGNR, DCSIGNR, DC-SIGN2, CLEC4M, CD209L
Anti-CD299 Monoclonal Antibody (2X91) 是一种 Mouse 抗体,靶向 CD299。Anti-CD299 Monoclonal Antibody (2X91) 可用于 WB,FCM。

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| 产品描述 | Anti-CD299 Monoclonal Antibody (2X91) is a Mouse antibody targeting CD299. Anti-CD299 Monoclonal Antibody (2X91) can be used in WB,FCM. |
| 别名 | L-SIGN, LSIGN, HP10347, DC-SIGNR, DCSIGNR, DC-SIGN2, CLEC4M, CD209L |
| Ig Type | IgG1 |
| 克隆号 | 2X91 |
| 反应种属 | Human |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/ml |
| 研究背景 | This gene encodes a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses, with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are common and have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 30835; often referred to as DC-SIGN or CD209). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human CD299 (AA: extra 237-399) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | CLEC4M |
| 基因ID | |
| 蛋白名称 | C-type lectin domain family 4 member M |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |