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Anti-CD299 Monoclonal Antibody (2X91)

Synonyms: L-SIGN, LSIGN, HP10347, DC-SIGNR, DCSIGNR, DC-SIGN2, CLEC4M, CD209L
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Anti-CD299 Monoclonal Antibody (2X91) 是一种 Mouse 抗体,靶向 CD299。Anti-CD299 Monoclonal Antibody (2X91) 可用于 WB,FCM。

Anti-CD299 Monoclonal Antibody (2X91)

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货号 TMAT-0358

别名 L-SIGN, LSIGN, HP10347, DC-SIGNR, DCSIGNR, DC-SIGN2, CLEC4M, CD209L

Anti-CD299 Monoclonal Antibody (2X91) 是一种 Mouse 抗体,靶向 CD299。Anti-CD299 Monoclonal Antibody (2X91) 可用于 WB,FCM。

Anti-CD299 Monoclonal Antibody (2X91)
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产品介绍


生物活性
产品描述
Anti-CD299 Monoclonal Antibody (2X91) is a Mouse antibody targeting CD299. Anti-CD299 Monoclonal Antibody (2X91) can be used in WB,FCM.
别名
L-SIGN, LSIGN, HP10347, DC-SIGNR, DCSIGNR, DC-SIGN2, CLEC4M, CD209L
Ig Type
IgG1
克隆号
2X91
反应种属
Human
应用WBFCM
推荐剂量
WB: 1/500-1/2000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景This gene encodes a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses, with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are common and have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 30835; often referred to as DC-SIGN or CD209). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human CD299 (AA: extra 237-399) expressed in E. Coli.
抗原种属
Human
基因名称
CLEC4M
基因ID
蛋白名称
C-type lectin domain family 4 member M
Uniprot ID
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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