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Anti-FOLR2 Antibody (6I902)

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Anti-FOLR2 Antibody (6I902)
产品编号 TMAY-01765
别名 β-HFR, FR-β, FR-P3, FR-BETA, folate receptor 2 (fetal), FBP/PL-1, FBP, BETA-HFR

Anti-FOLR2 Antibody (6I902) 是一种 Rabbit 抗体,靶向 FOLR2。Anti-FOLR2 Antibody (6I902) 可用于 IHC-P。

Anti-FOLR2 Antibody (6I902)
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Anti-FOLR2 Antibody (6I902)

Rating icon 还可以
Anti-FOLR2 Antibody (6I902)
产品编号 TMAY-01765 别名 β-HFR, FR-β, FR-P3, FR-BETA, folate receptor 2 (fetal), FBP/PL-1, FBP, BETA-HFR

Anti-FOLR2 Antibody (6I902) 是一种 Rabbit 抗体,靶向 FOLR2。Anti-FOLR2 Antibody (6I902) 可用于 IHC-P。

规格价格库存数量
100 μL
¥ 2,284
5日内发货
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产品介绍

生物活性
产品描述
Anti-FOLR2 Antibody (6I902) is a Rabbit antibody targeting FOLR2. Anti-FOLR2 Antibody (6I902) can be used in IHC-P.
别名β-HFR, FR-β, FR-P3, FR-BETA, folate receptor 2 (fetal), FBP/PL-1, FBP, BETA-HFR
Ig Type
Rabbit IgG
克隆号
6I902
交叉反应
Human
验证活性
1. Immunochemical staining of human FOLR2 in human spleen with rabbit monoclonal antibody at 1:5000 dilution,formalin-fixed paraffin embedded sections.
2. Immunochemical staining of human FOLR2 in human placenta with rabbit monoclonal antibody at 1:5000 dilution,formalin-fixed paraffin embedded sections.
应用
IHC-P
推荐剂量
IHC-P: 1:2000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human FOLR2 (rh FOLR2; TMPY-01280; P14207-1; Met1-His228).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potocytosis. FOLR2 has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. The FOLR2 protein was originally thought to exist only in placenta, but is also detected in spleen, bone marrow, and thymus. FOLR2 is a marker for macrophages generated in the presence of M-CSF, but not GM-CSF. Its expression correlates with increased folate uptake ability. Folate conjugates of therapeutic drugs are a potential immunotherapy tool to target tumor-associated macrophages.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human FOLR2 protein (TMPY-01280)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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