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Anti-FOLR2 Antibody (6I902)
还可以产品编号 TMAY-01765
Anti-FOLR2 Antibody (6I902) 是一种 Rabbit 抗体，靶向 FOLR2。Anti-FOLR2 Antibody (6I902) 可用于 IHC-P。
Anti-FOLR2 Antibody (6I902)
Anti-FOLR2 Antibody (6I902)
还可以产品编号 TMAY-01765
Anti-FOLR2 Antibody (6I902) 是一种 Rabbit 抗体，靶向 FOLR2。Anti-FOLR2 Antibody (6I902) 可用于 IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-FOLR2 Antibody (6I902) is a Rabbit antibody targeting FOLR2. Anti-FOLR2 Antibody (6I902) can be used in IHC-P. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 6I902 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human FOLR2 in human spleen with rabbit monoclonal antibody at 1:5000 dilution,formalin-fixed paraffin embedded sections. 2. Immunochemical staining of human FOLR2 in human placenta with rabbit monoclonal antibody at 1:5000 dilution,formalin-fixed paraffin embedded sections. |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:2000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human FOLR2 (rh FOLR2; TMPY-01280; P14207-1; Met1-His228). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potocytosis. FOLR2 has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. The FOLR2 protein was originally thought to exist only in placenta, but is also detected in spleen, bone marrow, and thymus. FOLR2 is a marker for macrophages generated in the presence of M-CSF, but not GM-CSF. Its expression correlates with increased folate uptake ability. Folate conjugates of therapeutic drugs are a potential immunotherapy tool to target tumor-associated macrophages. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human FOLR2 protein (TMPY-01280) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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