Kallikrein 1/KLK1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.3 kDa and the accession number is P15947.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
50 μg | ¥ 4,460 | 5日内发货 |
生物活性 | Measured by its ability to cleave a flourogenic peptide substrate Pro-Phe-Arg-7-amido-4-methylcoumarin(PFR-AMC). The specific activity is >6, 000 pmol/min/μg. (Activation description: The proenzyme needs to be activated by Thermolysin for an activated form) |
产品描述 | Kallikrein 1/KLK1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.3 kDa and the accession number is P15947. |
种属 | Mouse |
表达系统 | HEK293 Cells |
标签 | C-His |
蛋白编号 | P15947 |
别名 | Kal, mGk-6, Klk1b6, kallikrein 1, Klk6, 0610007D04Rik |
蛋白构建 | Mouse KLK1 (P15947) (Met1-Asp261) |
蛋白纯度 | > 90 % as determined by SDS-PAGE |
分子量 | 28.3 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing 25 mM Tris, 5 mM CaCl2, 0.15 M NaCl, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | KLK1 (Kallikrein 1) is a Protein Coding gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. Human tissue kallikrein (KLK1) is a serine protease, a component of the KKS that has been demonstrated to exert pleiotropic beneficial effects in protection from tissue injury through its anti-inflammatory, antiapoptotic, antifibrotic, and antioxidative actions. Polymorphism of the human tissue kallikrein 1 (KLK1) A1789G gene is associated with susceptibility to hypertension. Diseases associated with KLK1 include Kallikrein, Decreased Urinary Activity Of and Hereditary Angioedema. |
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Kallikrein 1/KLK1 Protein, Mouse, Recombinant (His) Kal mGk-6 Klk1b6 kallikrein 1 Klk6 0610007D04Rik recombinant recombinant-proteins proteins protein