Name: LILRB2/CD85d/ILT4 Domain1 & 2 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPK-01101
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 313

6-8日内发货

10 μg

¥ 498

6-8日内发货

20 μg

¥ 793

5日内发货

50 μg

¥ 1,580

5日内发货

100 μg

¥ 2,660

5日内发货

200 μg

¥ 4,790

5日内发货

500 μg

¥ 10,600

5日内发货

生物活性

产品描述	The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. LILRB2/CD85d/ILT4 Domain1 & 2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 24.2 kDa and the accession number is Q8N423-1.
生物活性	1. Immobilized Human LILRB2 Domain1&2, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-LILRB2 Antibody, hFc Tag with the EC50 of 16.6ng/ml determined by ELISA (QC Test). 2. Human HLA-G Complex Tetramer, His Tag immobilized on CM5 Chip can bind Human LILRB2 Domain1&2, His Tag with an affinity constant of 6.5μM as determined in a SPR assay.
研究背景	The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles.
种属	Human
表达系统	HEK293 Cells
标签	C-His
蛋白编号	Q8N423-1
蛋白构建	Gln22-Val229
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	MIR10, LIR2, LILRB2, ILT4CD85d, ILT-4, ILT4, CD85d
内毒素	< 1 EU/μg by the LAL method.

化学信息

分子量	24.2 kDa (predicted). Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result.

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

LILRB2/CD85d/ILT4 Domain1 & 2 Protein, Human, Recombinant (His)

LILRB2/CD85d/ILT4 Domain1 & 2 Protein, Human, Recombinant (His)

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