Anti-BDNF Antibody (1R78)

Name: Anti-BDNF Antibody (1R78)
Brand: TargetMol
SKU: TMAB-00207
Rating: 4.5 (1 reviews)

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产品编号 TMAB-00207

Anti-BDNF Antibody (1R78) 是一种 Rabbit 抗体，靶向 BDNF。Anti-BDNF Antibody (1R78) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-BDNF Antibody (1R78)

还可以

产品编号 TMAB-00207

Anti-BDNF Antibody (1R78) 是一种 Rabbit 抗体，靶向 BDNF。Anti-BDNF Antibody (1R78) 可用于 WB,IHC-P,IHC-Fr,IF。

规格	价格	库存
25 μL	¥ 785	5日内发货
50 μL	¥ 1,385	5日内发货
100 μL	¥ 2,495	5日内发货

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生物活性

产品描述	Anti-BDNF Antibody (1R78) is a Rabbit antibody targeting BDNF. Anti-BDNF Antibody (1R78) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type	IgG
克隆号	1R78
交叉反应	Human,Mouse,Rat
验证活性	1. 25 μg total protein per Lane of various lysates probed with BDNF monoclonal antibody, unconjugated (TMAB-00207) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min. 2. Paraformaldehyde-fixed, paraffin embedded Mouse Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with BDNF Monoclonal Antibody, Unconjugated (TMAB-00207) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded Rat Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with BDNF Monoclonal Antibody, Unconjugated (TMAB-00207) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 4. Paraformaldehyde-fixed, paraffin embedded Mouse Cerebellum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with BDNF Monoclonal Antibody, Unconjugated (TMAB-00207) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 5. Paraformaldehyde-fixed, paraffin embedded Rat Cerebellum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with BDNF Monoclonal Antibody, Unconjugated (TMAB-00207) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 6. Paraformaldehyde-fixed, paraffin embedded Rat Spinal Cord; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with BDNF Monoclonal Antibody, Unconjugated (TMAB-00207) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 7. Paraformaldehyde-fixed, paraffin embedded Human Left Parietal Lobe; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with BDNF Monoclonal Antibody, Unconjugated (TMAB-00207) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
应用	WB IHC-P IHC-Fr IF
推荐剂量	WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
抗体种类	Monoclonal
宿主来源	Rabbit
亚细胞定位	Secreted.
构建方式	Recombinant Antibody
纯化方式	Protein A purified
性状	Liquid
缓冲液	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景	Neurotrophins function to regulate naturally occurring cell death of neurons during development. The prototype neurotrophin is nerve growth factor (NGF), originally discovered in the 1950s as a soluble peptide promoting the survival of, and neurite outgrowth from, sympathetic ganglia. More recently, three additional structurally homologous neurotrophic factors have been identified. These include brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and neurotrophin-4 (NT-4), also designated NT-5. These various neurotrophins stimulate the in vitro survival of distinct but partially overlapping populations of neurons. The Trk A receptor is the preferential receptor for NGF, but also binds NT-3 and NT-4. The Trk B receptor binds equally well to both BDNF and NT-4 and to a lesser extent NT-3, while the Trk C receptor only binds NT-3. BDNF promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Belongs to the NGF-beta family.

抗原信息

免疫原	A synthesized peptide: human BDNF
抗原种属	Human
基因ID	627
Uniprot ID	P23560
研究领域	Diabetes associated,Thrombosis,Diabetes,Obesity,Neurotrophins,Alzheimer's disease,Huntington's disease,bdnf