S100A8 & S100A9 Heterodimer Protein, Human, Recombinant (His) is expressed in E. coli. The accession number is P05109 (S100A8) & P06702 (S100A9).

Human

E. coli

S100 calcium-binding protein A9,S100 calcium-binding protein A8,Protein S100-A9,Protein S100-A8,MRP-8,MRP-14,CFAG,Calgranulin-A

S100A8

> 95% as determined by Bis­Tris PAGE

Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.

Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

Calprotectin, a member of the widespread calcium-binding S-100 protein family, is present in remarkably high concentration in the cytoplasm of human neutrophils. The calprotectin molecule is composed of light (MRP8) and heavy (MRP14) subunits. Although not secreted from intact neutrophils, calprotectin release from dead and dying neutrophils creates high concentrations of the protein in inflammatory or abscess fluids and in the intestinal tract lumen of patients with inflammatory bowel disease.