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Anti-Sumo2/3 Antibody (4V504) 是一种 Rabbit 抗体,靶向 Sumo2/3。Anti-Sumo2/3 Antibody (4V504) 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM。
Anti-Sumo2/3 Antibody (4V504) 是一种 Rabbit 抗体,靶向 Sumo2/3。Anti-Sumo2/3 Antibody (4V504) 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 790 | 5日内发货 | |
| 50 μL | ¥ 1,395 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-Sumo2/3 Antibody (4V504) is a Rabbit antibody targeting Sumo2/3. Anti-Sumo2/3 Antibody (4V504) can be used in IHC-P,IHC-Fr,ICC/IF,IF,FCM. |
| Ig Type | IgG |
| 克隆号 | 4V504 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | IHC-PIHC-FrICC/IFIFFCM |
| 推荐剂量 | IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; FCM: 1μg/Test |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. Nucleus, PML body. |
| 组织特异性 | Broadly expressed. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Small ubiquitin-related modifier 1, 2 and 3 (SUMO-1, -2 and -3) are members of the ubiquitin-like protein family. The covalent attachment of the SUMO-1, -2 or -3 (SUMOylation) to target proteins is analogous to ubiquitination. This post-translational modification is a reversible, multi-step process that is initiated by cleaving a precursor protein to a mature protein. |
| 免疫原 | A synthesized peptide: human Sumo 2 |
| 抗原种属 | Human |
| 基因名称 | SUMO2 |
| 基因ID | |
| 蛋白名称 | Small ubiquitin-related modifier 2 |
| Uniprot ID | |
| 功能 | Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. |
| 分子量 | Theoretical: 11, 12 kDa. Actual: 16 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |