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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-GRAP Polyclonal Antibody

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货号 TMAB-06757

Anti-GRAP Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GRAP。Anti-GRAP Polyclonal Antibody 可用于 WB。

Anti-GRAP Polyclonal Antibody

Anti-GRAP Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06757

Anti-GRAP Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GRAP。Anti-GRAP Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-GRAP Polyclonal Antibody is a Rabbit antibody targeting GRAP. Anti-GRAP Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Cow,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Many growth factors function by binding receptors with intrinsic tyrosine kinase activity. Signaling by such receptors involves a series of intermediates characterized by SH2 domains that bind tyrosine phosphorylated receptors by a direct interaction between the SH2 domain and specific receptor sequences. For instance, the GRB family of proteins lack a defined catalytic activity and are entirely composed of SH2 and SH3 domains. Members include GRB2, GRB7, GRB10 (also referred to as GRB-IR), GRB14 and Grap (for GRB2-related adapter protein). While GRB10 and GRB14 are most closely related to GRB7, Grap shares the highest degree of homology with GRB2 exhibiting 59% sequence identity with GRB2. The Grap SH2 domain is capable of binding to the activated stem cell factor receptor, c-Kit and the erythropoietin receptor (EpoR). Grap also associates with the Ras guanine nucleotide exchange factor Sos 1 via its amino terminal SH3 domain.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GRAP
抗原种属
Human
基因名称
GRAP
基因ID
10750
蛋白名称
GRB2-related adapter protein
Uniprot ID
Q13588
功能
Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.
化学信息
分子量Theoretical: 25 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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