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IL-33 Protein, Rhesus macaque, Recombinant (His)

IL-33 Protein, Rhesus macaque, Recombinant (His)

产品编号 TMPJ-00617
别名: Interleukin-33, IL1F11, IL33, 白介素, 白细胞介素, IL-1F11, Interleukin-1 Family Member 11, C9orf26, NFHEV, IL-33, NF-HEV, Nuclear Factor From High Endothelial Venules

Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.

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IL-33 Protein, Rhesus macaque, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 1,170 5日内发货
50 μg ¥ 3,470 5日内发货
500 μg ¥ 13,200 5日内发货
1 mg ¥ 18,900 5日内发货
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产品目录号及名称: IL-33 Protein, Rhesus macaque, Recombinant (His) (TMPJ-00617)
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生物活性
技术参数
产品性质
生物活性 Immobilized Mouse ST2-His at 5μg/ml (100 μl/well)can bind Rhesus Macaque IL-33-His. The ED50 of Rhesus Macaque IL-33-His is 82.03 ng/ml. (Regularly tested)
产品描述 Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.
种属 Rhesus
表达系统 E. coli
标签 N-6xHis
蛋白编号 F7DLG4
别名 Interleukin-33, IL1F11, IL33, 白介素, 白细胞介素, IL-1F11, Interleukin-1 Family Member 11, C9orf26, NFHEV, IL-33, NF-HEV, Nuclear Factor From High Endothelial Venules
氨基酸序列 Ser112-Ile270
蛋白构建 Ser112-Ile270
分子量 21 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.

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Keywords

IL-33 Protein, Rhesus macaque, Recombinant (His) Interleukin-33 IL1F11 IL33 白介素 IL 33 白细胞介素 IL-1F11 Interleukin-1 Family Member 11 C9orf26 NFHEV IL-33 NF-HEV Nuclear Factor From High Endothelial Venules recombinant recombinant-proteins proteins protein

 

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