购物车
- 全部删除
您的购物车当前为空
Anti-SIGIRR Antibody-PE (6K128)
还可以产品编号 TMAY-02261P
Anti-SIGIRR Antibody-PE (6K128) 是一种 PE-conjugated Rabbit 抗体，靶向 SIGIRR。Anti-SIGIRR Antibody-PE (6K128) 可用于 FCM。
Anti-SIGIRR Antibody-PE (6K128)
Anti-SIGIRR Antibody-PE (6K128)
还可以产品编号 TMAY-02261P
Anti-SIGIRR Antibody-PE (6K128) 是一种 PE-conjugated Rabbit 抗体，靶向 SIGIRR。Anti-SIGIRR Antibody-PE (6K128) 可用于 FCM。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-SIGIRR Antibody-PE (6K128) is a PE-conjugated Rabbit antibody targeting SIGIRR. Anti-SIGIRR Antibody-PE (6K128) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 6K128 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human SIGIRR expression on SW480 cells. Cells were stained with PE-conjugated anti-Human SIGIRR. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human SIGIRR / TIR8 (rh SIGIRR / TIR8; TMPY-01894; Q6IA17-1; Met1-His118) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | Single Ig IL-1-related receptor (SIGIRR) or TIR8 is a member of Toll-like receptor-interleukin 1 receptor signaling (TLR-IL-1R) receptor superfamily. Although SIGIRR/TIR8 shows the typical conserved motifs that characterize the IL-1R and Toll superfamily, it is structurally and functionally distinct from both. SIGIRR/TIR8 has only one Ig domain in its extracellular portion whereas the IL-1R family contains three Ig folds. An unusually long cytoplasmic domain is reminiscent of the structure of drosophila Toll, yet the SIGIRR peptide sequence is more closely related to IL-1RI. SIGIRR/TIR8 was mainly expressed in mouse and human epithelial tissues such as kidney, lung and gut. Resting and activated T and B lymphocytes and monocytes-macrophages expressed little or no SIGIRR/TIR8, with the exception of the mouse GG2EE macrophage line. Inflammation is enhanced in SIGIRR-deficient mice. SIGIRR negatively modulates immune responses. Inflammation is enhanced in SIGIRR-deficient mice, as shown by their enhanced chemokine induction after IL-1 injection and reduced threshold for lethal endotoxin challenge. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human SIGIRR / TIR8 protein (TMPY-01894) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-SIGIRR Antibody-PE (6K128) | purchase Anti-SIGIRR Antibody-PE (6K128) | Anti-SIGIRR Antibody-PE (6K128) cost | order Anti-SIGIRR Antibody-PE (6K128)
嗨！有任何问题？点我咨询
评论内容