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Anti-Gremlin-1 Antibody (3L967)
还可以产品编号 TMAH-00512
别名 GREM1
Anti-Gremlin-1 Antibody (3L967) 是一种抗体，靶向 Gremlin-1。Anti-Gremlin-1 Antibody (3L967) 可用于 ELISA, IHC。
Anti-Gremlin-1 Antibody (3L967)
Anti-Gremlin-1 Antibody (3L967)
还可以产品编号 TMAH-00512 别名 GREM1
Anti-Gremlin-1 Antibody (3L967) 是一种抗体，靶向 Gremlin-1。Anti-Gremlin-1 Antibody (3L967) 可用于 ELISA, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,310 | 5日内发货 | |
| 100 μL | ¥ 2,180 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Gremlin-1 Antibody (3L967) is an antibody targeting Gremlin-1. Anti-Gremlin-1 Antibody (3L967) can be used in ELISA, IHC. |
| 别名 | GREM1 |
| Ig Type | hIgG1 |
| 克隆号 | 3L967 |
| 交叉反应 | Human |
| 验证活性 | 1. IHC image of TMAH-00512 diluted at 1：100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB. 2. IHC image of TMAH-00512 diluted at 1：100 and staining in paraffin-embedded human gastric cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB. |
| 应用 | ELISA, IHC |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Secreted. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| 研究背景 | Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human GREM1 Protein |
| 抗原种属 | Human |
| 基因ID | 26585 |
| Uniprot ID | |
| 研究领域 | Signal transduction, Stem cells |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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