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Anti-GFR alpha 3 Polyclonal Antibody

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货号 TMAB-06451

Anti-GFR alpha 3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GFR alpha 3。Anti-GFR alpha 3 Polyclonal Antibody 可用于 WB。

Anti-GFR alpha 3 Polyclonal Antibody

Anti-GFR alpha 3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06451

Anti-GFR alpha 3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GFR alpha 3。Anti-GFR alpha 3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-GFR alpha 3 Polyclonal Antibody is a Rabbit antibody targeting GFR alpha 3. Anti-GFR alpha 3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane.
组织特异性Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression. Very low or no expression detected in the hematopoietic system.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Glial cell line-derived neurotrophic factor (GDNF) and the related neurotrophic factor neurturin (NTN) are potent survival factors for central and peripheral neurons. GDNF is a glycosylated, disulfide-bonded homodimer that is distantly related to the TGF Beta superfamily of growth factors. Three receptors for these factors, GFR Alpha-1 (also designated GDNFR-Alpha, RETL1 or TrnR-1), GFR Alpha-2 (also designated GDNFR-Beta, RETL2, NTNR-Alpha or TrnR-2) and GFR Alpha-3 have been identified. The receptors do not contain transmembrane domains and are attached to the cell membrane by glycosyl-phosphoinositol linkage. Both GFR Alpha-1 and GFR Alpha-2 have been shown to mediate the GDNF-dependent and NTN-dependent phosphorylation and activation of the tyrosine kinase Ret. GFR Alpha-3 is expressed only during development.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GFR alpha 3
抗原种属
Human
基因名称
GFRA3
基因ID
蛋白名称
GDNF family receptor alpha-3
Uniprot ID
功能
Receptor for the glial cell line-derived neurotrophic factor, ARTN (artemin). Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase.
化学信息
分子量Theoretical: 38 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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