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Anti-NME1/NM23A Polyclonal Antibody 2

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货号 TMAB-09531

Anti-NME1/NM23A Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 NME1/NM23A。Anti-NME1/NM23A Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF,ELISA,WB。

Anti-NME1/NM23A Polyclonal Antibody 2

Anti-NME1/NM23A Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-09531

Anti-NME1/NM23A Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 NME1/NM23A。Anti-NME1/NM23A Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF,ELISA,WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
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产品介绍

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产品描述
Anti-NME1/NM23A Polyclonal Antibody 2 is a Rabbit antibody targeting NME1/NM23A. Anti-NME1/NM23A Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF,ELISA,WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用IHC-PIHC-FrIFELISAWB
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000; WB: 1:500 - 1:1000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Note=Cell-cycle dependent nuclear localization which can be induced by interaction with Epstein-barr viral proteins or by degradation of the SET complex by GzmA.
组织特异性Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation. Isoform 3 is ubiquitously expressed.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Nm23
抗原种属
Human
基因名称
NME1
基因ID
4830
蛋白名称
Nucleoside diphosphate kinase A
Uniprot ID
P15531
功能
Major role in the synthesis of nucleoside triphosphates other than ATP. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination.
化学信息
分子量Theoretical: 17 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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