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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-THAP1 Polyclonal Antibody

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货号 TMAB-13504

Anti-THAP1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 THAP1。Anti-THAP1 Polyclonal Antibody 可用于 WB。

Anti-THAP1 Polyclonal Antibody

Anti-THAP1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-13504

Anti-THAP1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 THAP1。Anti-THAP1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-THAP1 Polyclonal Antibody is a Rabbit antibody targeting THAP1. Anti-THAP1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Chicken,Dog,Cow,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus, nucleoplasm. Nucleus, PML body.
组织特异性Highly expressed in heart, skeletal muscle, kidney and liver. Weaker expression in brain and placenta.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景THAP1 contains a THAP domain, a zinc-dependent DNA-binding domain. It colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies and is a pro-apoptopic protein that potentiates both serum-withdrawal and TNF-induced apoptosis. It is a physiologic regulator of endothelial cell proliferation and cell-cycle progression, two essential processes for angiogenesis.
抗原信息
免疫原
KLH conjugated synthetic peptide: human THAP1
抗原种属
Human
基因名称
THAP1
基因ID
55145
蛋白名称
THAP domain-containing protein 1
Uniprot ID
Q9NVV9
功能
DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.
化学信息
分子量Theoretical: 25 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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