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Anti-IL-15 Antibody (5P630)
还可以产品编号 TMAY-00689
Anti-IL-15 Antibody (5P630) 是一种 Mouse 抗体，靶向 IL-15。Anti-IL-15 Antibody (5P630) 可用于 ELISA。
Anti-IL-15 Antibody (5P630)
Anti-IL-15 Antibody (5P630)
还可以产品编号 TMAY-00689
Anti-IL-15 Antibody (5P630) 是一种 Mouse 抗体，靶向 IL-15。Anti-IL-15 Antibody (5P630) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-IL-15 Antibody (5P630) is a Mouse antibody targeting IL-15. Anti-IL-15 Antibody (5P630) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 5P630 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL-15 / IL15 / Interleukin 15 (rh IL-15 / IL15 / Interleukin 15; TMPY-04049; NP_000576.1; Asn49-Ser162). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in 20 mM MES, 100 mM NaCl, 10% Trehalose, pH 6.0 |
| 研究背景 | The protein encoded by the IL15 gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietic receptor subunits and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively, spliced transcript variants of this gene have been reported.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human IL-15 / IL15 / Interleukin 15 Protein (TMPY-04049) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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