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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-RSPO1 Polyclonal Antibody

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货号 TMAB-12406

Anti-RSPO1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RSPO1。Anti-RSPO1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-RSPO1 Polyclonal Antibody

Anti-RSPO1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12406

Anti-RSPO1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 RSPO1。Anti-RSPO1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-RSPO1 Polyclonal Antibody is a Rabbit antibody targeting RSPO1. Anti-RSPO1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Dog,Pig,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Abundantly expressed in adrenal glands, ovary, testis, thyroid and trachea but not in bone marrow, spinal cord, stomach, leukocytes colon, small intestine, prostate, thymus and spleen.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景RSPO1 is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.
抗原信息
免疫原
KLH conjugated synthetic peptide: human RSPO1
抗原种属
Human
基因名称
RSPO1
基因ID
284654
蛋白名称
R-spondin-1
Uniprot ID
Q2MKA7
功能
Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway, possibly via a direct interaction with Wnt proteins, and in a Wnt-independent beta catenin pathway through a receptor signaling pathway that may not use frizzled/LRP receptors. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determination.
化学信息
分子量Theoretical: 27 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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