IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form)

IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form) is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession number is Q63264-1.

规格	价格/CNY		数量
20 μg	￥ 1,750	现货
100 μg	￥ 4,430	5日内发货
200 μg	￥ 7,850	5日内发货
500 μg	￥ 16,670	5日内发货

规格

价格/CNY

货期

数量

20 μg

￥ 1,750

现货

100 μg

￥ 4,430

5日内发货

200 μg

￥ 7,850

5日内发货

500 μg

￥ 16,670

5日内发货

生物活性	Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is typically 0.1-0.5 μg/mL.
产品描述	IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form) is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession number is Q63264-1.

种属	Rat
表达系统	E. coli
标签	Tag Free
蛋白编号	Q63264-1
别名	白细胞介素, interleukin 1, beta, 白介素, interleukin 1, β, IL-1 β
蛋白构建	The mature form of Rat IL1B (Q63264-1) (Val 117-Ser 268) was expressed and purified.
蛋白纯度	> 98 % as determined by SDS-PAGE
分子量	17.4 kDa (predicted)

内毒素	Please contact us for more information.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 40 mM Tris, 0.15 M NaCl, pH 7.8. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of a successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc).Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy