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Anti-TIE2 Antibody (7A105)

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Anti-TIE2 Antibody (7A105)
产品编号 TMAY-01086
别名 Tie-2, Tie2, TEK tyrosine kinase, endothelial, STK1, Hyk, Cd202b, AA517024

Anti-TIE2 Antibody (7A105) 是一种 Mouse 抗体,靶向 TIE2。Anti-TIE2 Antibody (7A105) 可用于 ELISA。

Anti-TIE2 Antibody (7A105)

Anti-TIE2 Antibody (7A105)

Rating icon 还可以
Anti-TIE2 Antibody (7A105)
产品编号 TMAY-01086 别名 Tie-2, Tie2, TEK tyrosine kinase, endothelial, STK1, Hyk, Cd202b, AA517024

Anti-TIE2 Antibody (7A105) 是一种 Mouse 抗体,靶向 TIE2。Anti-TIE2 Antibody (7A105) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,679
5日内发货
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产品介绍

生物活性
产品描述
Anti-TIE2 Antibody (7A105) is a Mouse antibody targeting TIE2. Anti-TIE2 Antibody (7A105) can be used in ELISA.
别名Tie-2, Tie2, TEK tyrosine kinase, endothelial, STK1, Hyk, Cd202b, AA517024
Ig Type
Mouse IgG2b
克隆号
7A105
交叉反应
Human
应用
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TIE2 (rh TIE2; TMPY-01064; AAA61139.1; Met 1-Lys 745). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景TEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play critical roles in vascular maturation, maintenance of integrity and remodeling. Targeted mutagenesis of both Tek and its agonistic ligand, Angiopoietin-1, result in embryonic lethality, demonstrating that the signal transduction pathways mediated by this receptor are crucial for normal embryonic development. TEK signaling is indispensable for the development of the embryonic vasculature and suggests that TEK signaling may also be required for the development of the tumor vasculature.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human TIE2 protein (TMPY-01064)
抗原种属
Human
研究领域
Receptor Tyrosine Kinases (RTKs), Cancer Drug Targets, Hemangioblast Markers
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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