Anti-Centaurin gamma 1 Polyclonal Antibody is a Rabbit antibody targeting Centaurin gamma 1. Anti-Centaurin gamma 1 Polyclonal Antibody can be used in WB.

IgG

Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse)

WB: 1:500-2000

Polyclonal

KLH conjugated synthetic peptide: human Centaurin gamma 1

Human

AGAP2

Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent trafficking of proteins in the endosomal system. It seems to be oncogenic. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion.