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Anti-MKP-3 Antibody (2L119) 是一种 Mouse 抗体,靶向 MKP-3。Anti-MKP-3 Antibody (2L119) 可用于 WB,IP,IF,IHC-P。
Anti-MKP-3 Antibody (2L119) 是一种 Mouse 抗体,靶向 MKP-3。Anti-MKP-3 Antibody (2L119) 可用于 WB,IP,IF,IHC-P。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,980 | 5日内发货 | |
100 μL | ¥ 2,990 | 5日内发货 |
产品描述 | Anti-MKP-3 Antibody (2L119) is a Mouse antibody targeting MKP-3. Anti-MKP-3 Antibody (2L119) can be used in WB,IP,IF,IHC-P. |
别名 | Serine/threonine specific protein phosphatase, PYST1, PYST 1, MKP3, Mitogen-activated protein kinase phosphatase 3, Mitogen activated protein kinase phosphatase 3, MAP kinase phosphatase 3, hide, HH19, DUSP6a, Dusp6, DUSP 6a, DUSP 6, DUS6_HUMAN, Dual specificity protein phosphatase PYST1, Dual specificity protein phosphatase 6, Dual specificity phosphatase 6 isoform a, Dual specificity phosphatase 6 |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of MKP-3 expression in non-transfected (A) and human MKP-3 transfected (B) 293T whole cell lysates. 2. Immunoperoxidase staining of formalin fixed, paraffin-embedded human bronchus tissue showing cytoplasmic staining of respiratory epithelial cells. |
应用 | |
推荐剂量 | WB: 1:100-1000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X, and MKP-4. Human MKP-3 maps to chromosome 12q21.33 and encodes a 381 amino acid protein that specifically inactivates members of the ERK family and is expressed in a variety of tissues with the highest levels in heart and pancreas. |
偶联 | Unconjugated |
免疫原 | Peptide |
Uniprot ID |
分子量 | Theoretical: 42 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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