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Anti-MKP-3 Antibody (2L119)

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Anti-MKP-3 Antibody (2L119)
产品编号 TMAC-02600
别名 Serine/threonine specific protein phosphatase, PYST1, PYST 1, MKP3, Mitogen-activated protein kinase phosphatase 3, Mitogen activated protein kinase phosphatase 3, MAP kinase phosphatase 3, hide, HH19, DUSP6a, Dusp6, DUSP 6a, DUSP 6, DUS6_HUMAN, Dual specificity protein phosphatase PYST1, Dual specificity protein phosphatase 6, Dual specificity phosphatase 6 isoform a, Dual specificity phosphatase 6

Anti-MKP-3 Antibody (2L119) 是一种 Mouse 抗体,靶向 MKP-3。Anti-MKP-3 Antibody (2L119) 可用于 WB,IP,IF,IHC-P。

Anti-MKP-3 Antibody (2L119)

Anti-MKP-3 Antibody (2L119)

Rating icon 还可以
Anti-MKP-3 Antibody (2L119)
产品编号 TMAC-02600 别名 Serine/threonine specific protein phosphatase, PYST1, PYST 1, MKP3, Mitogen-activated protein kinase phosphatase 3, Mitogen activated protein kinase phosphatase 3, MAP kinase phosphatase 3, hide, HH19, DUSP6a, Dusp6, DUSP 6a, DUSP 6, DUS6_HUMAN, Dual specificity protein phosphatase PYST1, Dual specificity protein phosphatase 6, Dual specificity phosphatase 6 isoform a, Dual specificity phosphatase 6

Anti-MKP-3 Antibody (2L119) 是一种 Mouse 抗体,靶向 MKP-3。Anti-MKP-3 Antibody (2L119) 可用于 WB,IP,IF,IHC-P。

规格价格库存数量
50 μL
¥ 1,980
5日内发货
100 μL
¥ 2,990
5日内发货
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产品介绍

生物活性
产品描述
Anti-MKP-3 Antibody (2L119) is a Mouse antibody targeting MKP-3. Anti-MKP-3 Antibody (2L119) can be used in WB,IP,IF,IHC-P.
别名Serine/threonine specific protein phosphatase, PYST1, PYST 1, MKP3, Mitogen-activated protein kinase phosphatase 3, Mitogen activated protein kinase phosphatase 3, MAP kinase phosphatase 3, hide, HH19, DUSP6a, Dusp6, DUSP 6a, DUSP 6, DUS6_HUMAN, Dual specificity protein phosphatase PYST1, Dual specificity protein phosphatase 6, Dual specificity phosphatase 6 isoform a, Dual specificity phosphatase 6
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of MKP-3 expression in non-transfected (A) and human MKP-3 transfected (B) 293T whole cell lysates.
2. Immunoperoxidase staining of formalin fixed, paraffin-embedded human bronchus tissue showing cytoplasmic staining of respiratory epithelial cells.
应用
推荐剂量
WB: 1:100-1000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X, and MKP-4. Human MKP-3 maps to chromosome 12q21.33 and encodes a 381 amino acid protein that specifically inactivates members of the ERK family and is expressed in a variety of tissues with the highest levels in heart and pancreas.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Peptide
Uniprot ID
化学信息
分子量Theoretical: 42 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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