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Anti-Progesterone Receptor Antibody (9Z37)
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产品编号 TMAC-03435
别名 Progestin receptor form B, Progestin receptor form A, Progesterone receptor, PRGR, PRB, PRA, PR, PGR, Nuclear receptor subfamily 3 group C member 3, NR3C3
Anti-Progesterone Receptor Antibody (9Z37) 是一种 Rabbit 抗体，靶向 Progesterone Receptor。Anti-Progesterone Receptor Antibody (9Z37) 可用于 WB,ICC/IF,IHC,IP。
Anti-Progesterone Receptor Antibody (9Z37)
Anti-Progesterone Receptor Antibody (9Z37)
还可以产品编号 TMAC-03435 别名 Progestin receptor form B, Progestin receptor form A, Progesterone receptor, PRGR, PRB, PRA, PR, PGR, Nuclear receptor subfamily 3 group C member 3, NR3C3
Anti-Progesterone Receptor Antibody (9Z37) 是一种 Rabbit 抗体，靶向 Progesterone Receptor。Anti-Progesterone Receptor Antibody (9Z37) 可用于 WB,ICC/IF,IHC,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,485 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
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| 产品描述 | Anti-Progesterone Receptor Antibody (9Z37) is a Rabbit antibody targeting Progesterone Receptor. Anti-Progesterone Receptor Antibody (9Z37) can be used in WB,ICC/IF,IHC,IP. |
| 别名 | Progestin receptor form B, Progestin receptor form A, Progesterone receptor, PRGR, PRB, PRA, PR, PGR, Nuclear receptor subfamily 3 group C member 3, NR3C3 |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-Progesterone Receptor antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-Progesterone Receptor antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-Progesterone Receptor antibody. Counter stained with hematoxylin. 4. ICC staining Progesterone Receptor in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The effects of progesterone are mediated by two functionally different isoforms of the progesterone receptor, PR-A and PR-B, which are transcribed from distinct, estrogen-inducible promoters within a single copy of the PR gene. The first 164 amino acids of PR-B are absent in PR-A. Progesterone-bound PR-A and PR-B have different transcription activation properties. Specifically, PR-B functions as a transcriptional activator in most cell and promoter contexts, while PR-A is transcriptionally inactive and functions as a strong ligand-dependent transdominant repressor of steroid hormone receptor transcriptional activity. An inhibitory domain (ID), which maps to the amino terminus of the receptor, exists within both PR isoforms. Interestingly, the ID is functionally active only in PR-A and is necessary for steroid hormone transrepression by PR-A, suggesting that PR-A and PR-B may have different conformations in the cell. Phosphorylation of human PR occurs on at least nine serine residues. Phosphorylation of three of the residues is hormone-inducible (Ser 102, Ser 294 and Ser 345); the others are basal but hormone-stimulated. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 99 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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